A prospective evaluation of methylene blue and gentian violet dressing for management of chronic wounds with local infection.

International Wound Journal
Kevin Y Woo, Jolene Heil

Abstract

The objective of this prospective, non-randomised study was to evaluate the performance of an antibacterial foam dressing containing methylene blue and gentian violet (Hydrofera Blue Classic dressing® ) for the management of chronic wounds with local infection. Patients in this study were ≥18 years of age (n = 29), and each had at least one chronic wound ≥1 cm2 in size that showed signs of localised infection or critical colonisation but with good potential for healing based on clinical assessment. To all of these wounds, the dressing was applied and changed three times per week over the 4-week study period. The primary endpoints of the study were: (i) changes in wound surface area measurement, (ii) changes in Pressure Ulcer Scale for Healing (PUSH) scores, (iii) changes in percent surface area of devitalised tissue (i.e., yellow slough or other necrotic tissue) and (iv) changes in clinical signs associated with localised wound infection/critical colonisation. Participants were evaluated at presentation (week 0 = baseline), week 2 and at week 4 (end of the study). The 29 patients completed the study, and at week 4, the following wound improvements were observed: (i) baseline mean wound surface area was significantly reduced by ...Continue Reading

References

Nov 28, 2001·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·N A StottsJ Maklebust
Oct 20, 2004·Archives of Dermatology·Liliana SaapAnita Pedvis-Leftick
Mar 3, 2005·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Sue E GardnerChingwei D Shin
Feb 1, 1944·Journal of Bacteriology·C E Hoffmann, O Rahn
May 1, 1949·Journal of Bacteriology·W P Van Eseltine, O Rahn
Aug 31, 2006·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Rebecca S Howell-JonesDavid W Thomas
Jun 23, 2007·Journal of Wound, Ostomy, and Continence Nursing : Official Publication of the Wound, Ostomy and Continence Nurses Society·D W Brett
Dec 27, 2007·Journal of the American Academy of Dermatology·Kathryn A Gehrig, Erin M Warshaw
May 23, 2008·International Wound Journal·Anita E Saltmarche
Aug 30, 2008·Journal of Wound Care·R D WolcottS E Dowd
Nov 12, 2009·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Chandan K SenMichael T Longaker
May 25, 2011·Journal of Wound, Ostomy, and Continence Nursing : Official Publication of the Wound, Ostomy and Continence Nurses Society·Sue E GardnerRita A Frantz
May 30, 2012·International Wound Journal·Philip G BowlerSamantha A Jones
Sep 4, 2012·The Western Journal of Emergency Medicine·Jonathan H ShahbazianKodi K Azari
Nov 5, 2013·Diabetes Care·J Bradford RiceNathan B Parsons
Sep 5, 2015·Advances in Wound Care·Robert G Frykberg, Jaminelli Banks
Feb 1, 1998·Journal of Wound Care·R Cooper, J C Lawrence
Aug 7, 2014·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Gisela Solange AlvarezMartin Federico Desimone

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Citations

Oct 18, 2018·Journal of Wound Care·Kevin WooDieter O Mayer
Jan 31, 2019·International Wound Journal·Ut T BuiHelen Edwards
Oct 23, 2020·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Louis ThesnaarTheunis T Cloete
May 19, 2021·Journal of Wound, Ostomy, and Continence Nursing : Official Publication of the Wound, Ostomy and Continence Nurses Society
Jul 29, 2021·Journal of Applied Microbiology·Andreea-Gabriela NedeleaSarah E Maddocks

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Statistical Package for Social Science ( SPSS )
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