A prospective, multi-center study: factors related to the management of diabetic foot infections.

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
B M ErtugrulF Akin

Abstract

The Turkish Association of Clinical Microbiology and Infectious Diseases, Diabetic Foot Infections Working Group conducted a prospective study to determine the factors affecting the outcomes of diabetic foot infections. A total of 96 patients were enrolled in the study. Microbiological assessment was performed in 86 patients. A total of 115 causative bacteria were isolated from 71 patients. The most frequently isolated bacterial species was Pseudomonas aeruginosa (n = 21, 18.3%). Among cases with bacterial growth, 37 patients (43%) were infected with 38 (33%) antibiotic-resistant bacteria. The mean (±SD) antibiotics cost was 2,220.42 (±994.59) USD in cases infected with resistant bacteria, while it was 1,206.60 (±1,160.6) USD in patients infected with susceptible bacteria (p < 0.001). According to the logistic regression analysis, the risk factors related to the growth of resistant bacteria were previous amputation (p = 0.018, OR = 7.229) and antibiotics administration within the last 30 days (p = 0.032, OR = 3.796); that related to the development of osteomyelitis was wound size >4.5 cm(2) (p = 0.041, OR = 2.8); and that related to the failure of the treatment was the growth of resistant bacteria (p = 0.016, OR = 5.333). Diabe...Continue Reading

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Citations

Oct 11, 2012·Diabetic Foot & Ankle·Abubakr H WidatallaMohamed Elmakki Ahmed
Jan 24, 2014·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·M HatipogluB A Lipsky
May 13, 2014·Photodiagnosis and Photodynamic Therapy·João Paulo TardivoMauricio S Baptista
Sep 20, 2015·Diabetes/metabolism Research and Reviews·Benjamin A LipskyEdgar J G Peters
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Dec 19, 2017·Journal of the American Podiatric Medical Association·Bulent M ErtugrulSerhan Sakarya
Mar 8, 2014·Clinics in Orthopedic Surgery·Laura Prieto-PérezJaime Esteban
Apr 7, 2019·Diabetes/metabolism Research and Reviews·Pinar SenBusra Emir
Jul 20, 2019·Foot & Ankle International·Nima HeidariRyan Rogero
Feb 14, 2020·Expert Review of Anti-infective Therapy·Bülent ErtuğrulBenjamin A Lipsky
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Sep 24, 2021·Frontiers in Microbiology·Jean-Philippe LavigneAlbert Sotto
Oct 9, 2021·Frontiers in Medicine·Wei ChaiXuezhi Li

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