PMID: 7542818Aug 1, 1995Paper

A prospective randomized comparison of transurethral resection to visual laser ablation of the prostate for the treatment of benign prostatic hyperplasia

Urology
R S CowlesA Zabbo

Abstract

Transurethral resection of the prostate (TURP) represents the accepted standard of surgical therapy for the management of symptomatic bladder outlet obstruction due to benign prostatic hyperplasia (BPH). However, this is a major operative procedure associated with significant perioperative morbidity. Visual laser ablation of the prostate (VLAP) utilizing a neodymium:yttrium-aluminum-garnet laser represents a new technologic approach to the surgical management of BPH. We compared the relative safety and efficacy of these two surgical approaches in a prospective, randomized trial. At 6 investigational sites in the United States, 115 men with symptomatic BPH more than 50 years of age and not in retention, were randomly assigned to undergo either TURP (59 patients) of VLAP (56 patients). VLAP patients received a mean of 10,200 J of energy delivered in a mean of 5.5 intraprostate laser applications. At preoperative baseline, 3 months, 6 months, and 1 year postoperatively, all patients underwent clinical evaluations, including ultrasonic prostatic volume determination, standardized American Urological Association (AUA)-6 symptom score, peak urine flow, postvoid residual urine volume, and quality-of-life assessment. Compared to TURP, ...Continue Reading

References

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Citations

Mar 7, 2006·World Journal of Urology·Ehab A Elzayat, Mostafa M Elhilali
Mar 3, 2007·International Urology and Nephrology·Emerson Luís Zani, Nelson Rodrigues Netto
Jun 27, 2002·Current Urology Reports·T A McNicholas, S Singh
Jun 28, 2005·Current Urology Reports·Werner W Hochreiter, Roger M Müller
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Jun 22, 2007·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Hashim U AhmedAmir V Kaisary
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Aug 27, 2011·Therapeutic Advances in Urology·Amir Zarrabi, Andreas J Gross
Nov 26, 2009·Patient Preference and Adherence·Jaspreet S Sandhu

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