A prospective, randomized, double-blinded comparison of ropivacaine 0.5%, 0.75%, and 1% ropivacaine for peribulbar block

Journal of Clinical Anesthesia
Luigi GioiaGianluigi Bolognesi

Abstract

To evaluate the efficacy of three different concentrations of ropivacaine (0.5%, 0.75%, and 1%) together with a single concentration of hyaluronidase administered for peribulbar block. Prospective, randomized, double-blind study. Anesthesia department of a university teaching hospital. 68 ASA physical status I, II, and III patients undergoing elective cataract surgery. Patients were randomly allocated to receive peribulbar block with 6.5 mL of either 0.5% (Group Ropi-5; n = 22), 0.75% (Group Ropi-7.5; n = 22), or 1% ropivacaine (Group Ropi-10; n = 24). In all patients, 0.5 mL of hyaluronidase was added to the local anesthetic solution. A larger proportion of patients in Groups Ropi-7.5 (82%) and Ropi-10 (83%) showed complete motor block 15 minutes after injection compared with Group Ropi-5 (55%;p = 0.05, andp = 0.03, respectively). Hypotension (reduction of systolic blood pressure by 30% or more from baseline) was observed in two Group Ropi-5 patients (9%), and two Group Ropi-7.5 patients (9%;p = 0.31), whereas bradycardia (reduction in heart rate < or = 50 bpm) was observed in one Group Ropi-5 patient (4%), and three Group Ropi-10 patients (12%;p = 0.18). Seven hours after surgery, a smaller proportion of Group Ropi-10 patient...Continue Reading

References

Jan 1, 1989·Archives of Ophthalmology·J L Weiss, C B Deichman
Jul 1, 1986·Journal of Cataract and Refractive Surgery·M R Mandel
Nov 1, 1986·Journal of Cataract and Refractive Surgery·L B Bloomberg
Sep 24, 1999·Acta Anaesthesiologica Scandinavica·J R NocitiA M Nunes

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Citations

Sep 25, 2010·Revista brasileira de anestesiologia·Catia Sousa Govêia, Edno Magalhães
Feb 8, 2006·European Journal of Oral Sciences·Nilton E OliveiraElisardo C Vasquez
Apr 4, 2021·Medicina·Michał Jan StasiowskiBeniamin Oskar Grabarek

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