A prospective, randomized, open and comparative study to evaluate the safety and efficacy of blue light treatment versus a topical benzoyl peroxide 5% formulation in patients with acne grade II and III

Anais Brasileiros De Dermatologia
Lúcia H F de ArrudaCarla Bassanezi Mazzaro

Abstract

Many acne patients improve after exposure to sunlight and there are many reports about the efficacy of blue light phototherapy on acne lesions. The purpose of this study was to evaluate efficacy and safety of blue light treatment versus topical benzoyl peroxide 5% formulation in patients with acne grades II and III. Sixty volunteers with facial acne were included and evaluated in 5 visits: the first one for screening, another 3 held on days 7, 14 and 28 of treatment, and the last one after 14 days of the end of treatment. Thirty of them were irradiated with Blue Light (8 times, twice a week) and the other thirty were treated with topical Benzoyl Peroxide 5% formulation, auto-applied twice a day, every day. We assessed the severity of acne by counting the lesions and analyzing the photographs. The improvement achieved by the blue light was the same as the one with benzoyl peroxide, regardless of the type of lesion (p 0.05). Otherwise, the side effects were less frequent in the group treated with blue light. Blue light irradiation was as effective as benzoyl peroxide in acne treatment grades II and III but there were fewer side effects.

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Citations

Aug 20, 2016·Dermatology and Therapy·Theresa N CanavanBoni E Elewski
Sep 28, 2016·The Cochrane Database of Systematic Reviews·Jelena BarbaricJosip Car
Oct 21, 2016·Journal of Cosmetic and Laser Therapy : Official Publication of the European Society for Laser Dermatology·Monique Narciso AlbaDenise Grotto
Mar 25, 2017·The British Journal of Dermatology·J BarbaricJ Car
Aug 3, 2018·Drug Development Research·Michael R Hamblin, Heidi Abrahamse
Feb 24, 2015·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Meghan T HessionEmmy M Graber

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