PMID: 9660024Jul 11, 1998Paper

A prospective, randomized trial comparing laparoscopic versus conventional techniques in colorectal cancer surgery: a preliminary report

Journal of the American College of Surgeons
J W MilsomP Elson

Abstract

Uncontrolled studies using laparoscopic techniques in colorectal surgery have not demonstrated clear advantages to these procedures compared with conventional ones, and surgeons are concerned about unusual early recurrences reported after laparoscopic colorectal cancer surgery. We conducted a prospective, randomized trial in one surgical department comparing laparoscopic (LAP) and conventional (CON) techniques in 109 patients undergoing bowel resection for colorectal cancers or polyps. Postoperatively, all patients underwent measurement of pulmonary function tests every 12 hours, and were treated identically on a highly controlled protocol with regard to analgesic administration, feeding, and postoperative care. Of the 55 patients assigned to LAP and 54 to the CON group, there were 42 and 38 with cancer, respectively (the other patients had large adenomas). Overall recovery of 80% of forced expiratory volume in 1 second and forced vital capacity was a median of 3 days for LAP and 6.0 days for CON (p = 0.01). LAP patients used significantly less morphine than CON patients up to the second day after surgery (0.78 +/- 0.32 versus 0.92 +/- 0.34 mg/kg per day, p = 0.02). Flatus returned a median of 3.0 days after LAP versus 4.0 days...Continue Reading

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Citations

Dec 14, 2004·The British Journal of Surgery·P KienleM W Büchler
Mar 10, 2001·Seminars in Surgical Oncology·M R Weiser, J W Milsom
May 27, 1999·Diseases of the Colon and Rectum·L Ruo, J G Guillem
Mar 3, 2001·Diseases of the Colon and Rectum·K NishiguchiN Tanigawa
Jan 24, 2002·Diseases of the Colon and Rectum·D HongM Anvari
Nov 24, 1999·Diseases of the Colon and Rectum·A J KyJ W Milsom
Mar 25, 2000·Diseases of the Colon and Rectum·L StocchiD M Ilstrup
Mar 2, 2005·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·T LierschH Becker
Dec 23, 2004·International Journal of Colorectal Disease·Guido WoesteC Wullstein
Apr 1, 2005·International Journal of Colorectal Disease·S O BreukinkW J H J Meijerink
Aug 2, 2005·International Journal of Colorectal Disease·S O BreukinkW J H J Meijerink
Apr 2, 2008·International Journal of Colorectal Disease·Y S LeeY H Kim
Oct 19, 2010·International Journal of Colorectal Disease·Wieland RaueWolfgang Schwenk
Jan 16, 2010·Langenbeck's Archives of Surgery·Alois FürstAyman Agha
Jul 10, 2001·Surgical Endoscopy·P A SeshadriE C Poulin
Oct 1, 2004·Surgical Endoscopy·R VeldkampUNKNOWN European Association of Endoscopic Surgery (EAES)
Mar 26, 2005·Surgical Endoscopy·Y W NovitskyM P Callery
Jul 26, 2006·Surgical Endoscopy·S KitanoUNKNOWN Japanese Laparoscopic Surgery Study Group
Feb 8, 2007·Surgical Endoscopy·D WeizmanD R Urbach
May 25, 2007·Surgical Endoscopy·Michelle A OstadiDavid R Urbach
Aug 21, 2007·Surgical Endoscopy·Takeshi NaitohYasuhiro Hasegawa
Feb 5, 2008·Surgical Endoscopy·Jason A Kemp, Samuel R G Finlayson
Apr 23, 2011·Surgical Endoscopy·Hajime KayanoNobuhiko Tanigawa
Dec 20, 2011·Surgical Endoscopy·Patrizia BertoGianluigi Melotti

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