A prospective study for treatment of nasal valve collapse due to lateral wall insufficiency: Outcomes using a bioabsorbable implant

The Laryngoscope
Pablo StolovitzkySam P Most

Abstract

To examine 6-month outcomes for treatment of lateral nasal wall insufficiency with a bioabsorbable implant. Prospective, multicenter, nonrandomized, single-blinded study. One hundred and one patients with severe-to-extreme class of Nasal Obstruction Symptom Evaluation (NOSE) scores were enrolled at 14 U.S. clinics (September 2016-March 2017). Patients were treated with a bioabsorbable implant designed to support lateral wall, with or without concurrent septoplasty and/or turbinate reduction procedure(s). NOSE scores and visual analog scale (VAS) were measured at baseline and month 1, 3, and 6 postoperatively. The Lateral Wall Insufficiency (LWI) score was determined by independent physicians observing the lateral wall motion video. Forty-three patients were treated with implant alone, whereas 58 had adjunctive procedures. Seventeen patients reported 19 adverse events, all of which resolved with no clinical sequelae. Patients showed significant reduction in NOSE scores at 1, 3, and 6 months postoperatively (79.5 ± 13.5 preoperatively, 34.6 ± 25.0 at 1 month, 32.0 ± 28.4 at 3 months, and 30.6 ± 25.8 at 6 months postoperatively; P < 0.01 for all). They also showed significant reduction in VAS scores postoperatively (71.9 ± 18.8 pr...Continue Reading

References

May 1, 1985·The Laryngoscope·R L Goode
Dec 1, 1996·Archives of Otolaryngology--head & Neck Surgery·R C Paniello
Mar 3, 2004·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Michael G StewartMaureen T Hannley
Apr 1, 2004·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Michael G StewartJonas T Johnson
Oct 27, 2006·American Journal of Rhinology·Derek J LamEdward M Weaver
May 23, 2007·Archives of Facial Plastic Surgery·Scott B Roofe, Sam P Most
Nov 20, 2008·Archives of Facial Plastic Surgery·Sam P Most
Jul 14, 2010·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·John S RheeDanielle DiVittorio
May 3, 2012·The Laryngoscope·Robin W Lindsay
Jul 13, 2013·JAMA Facial Plastic Surgery·Michael J Lipan, Sam P Most
Oct 15, 2013·Allergy & Rhinology·Gabriel J TsaoSam P Most
Sep 23, 2014·Plastic Surgery International·Elaine FungS Mark Taylor
Apr 18, 2015·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Josh SurowitzSam P Most
Jul 13, 2016·Facial Plastic Surgery Clinics of North America·Jarrod Keeler, Sam P Most
Apr 8, 2017·Facial Plastic Surgery : FPS·Marion San NicolóAlexander Berghaus
Aug 25, 2017·JAMA Facial Plastic Surgery·Reza VaezeafsharSam P Most
Mar 16, 2018·JAMA Facial Plastic Surgery·Cherian K KandathilMikhail Saltychev
Sep 19, 2018·Facial Plastic Surgery : FPS·Marion San NicolóAlexander Berghaus

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Citations

Jun 22, 2019·International Forum of Allergy & Rhinology·Pablo StolovitzkyDouglas M Sidle
Jun 25, 2019·Current Opinion in Otolaryngology & Head and Neck Surgery·Osan Y M HoMichael C F Tong
Jan 11, 2020·The Laryngoscope·Marshall GeElisabeth H Ference
Jun 17, 2020·OTO Open : the Official Open Access Journal of the American Academy of Otolaryngology--Head and Neck Surgery Foundation·Anais RameauPeter Luke Santa Maria
Apr 15, 2021·Facial Plastic Surgery : FPS·Douglas M SidleStacey Silvers
Jun 19, 2021·Facial Plastic Surgery & Aesthetic Medicine·Theodore V NguyenBrian J F Wong
Jun 26, 2021·American Journal of Otolaryngology·Michael D Olson, Jose E Barrera

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Clinical Trials Mentioned

NCT02952313
NCT02964312

Software Mentioned

R
SAS

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