A prospective study of infections in hemodialysis patients: patient hygiene and other risk factors for infection

Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America
L G KaplowitzC G Mayhall

Abstract

We performed a prospective randomized study on 71 patients on chronic outpatient hemodialysis to determine whether a sterile technique was better than a clean technique for preparation of the skin over the vascular access site prior to cannulation. In addition, we wanted to determine overall and site-specific infection rates, microbial etiologies of infection, and risk factors for infection. The overall infection rate was 4.7 infections per 100 dialysis months; the vascular access-site infection rate was 1.3 infections per 100 dialysis months; and the rate for bacteremia was 0.7 cases per 100 dialysis months. Staphylococcus aureus was the most common pathogen, but infections were equally divided between gram-positive cocci and gram-negative bacilli. Advanced age (P = 0.02), a low Karnofsky activity score (P = 0.05), poor hygiene (P = 0.0004) and number of hospitalizations (P = 0.0002) were risk factors for infections in general while only poor hygiene (P = 0.002) was a risk factor for vascular access-site infection. Sterile preparation of the skin over the vascular access site was no more effective at preventing infection than was clean technique (P = 0.80). Maintenance of good personal hygiene may be one of the most important ...Continue Reading

Citations

Aug 10, 2006·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Ali Mirza OnderGaston Zilleruelo
Nov 13, 2004·Current Infectious Disease Reports·Philip M Polgreen, L A Herwaldt
Sep 26, 2001·Infectious Disease Clinics of North America·S J Berman
Sep 26, 2001·Infectious Disease Clinics of North America·A H Cheung, L M Wong
Sep 26, 2001·Infectious Disease Clinics of North America·Jerome I TokarsMiriam J Alter
Apr 26, 2007·Nature Clinical Practice. Nephrology·Ratnaja Katneni, S Susan Hedayati
Feb 23, 1999·Kidney International·N R PoweW Briggs
Jun 26, 2001·Kidney International·G M Nassar, J C Ayus
Mar 11, 2004·Seminars in Vascular Surgery·Sean V RyanMatthew J Dougherty
May 7, 2010·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Petr BachledaJosef Zadrazil
Sep 26, 2008·Néphrologie & thérapeutique·Louis AyzacMarc Uzan
Oct 29, 2003·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Jay L XueAllan J Collins
Aug 1, 1994·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·S J Schwab
Sep 1, 1990·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·A H MossD E McDowell
Sep 2, 2008·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Jean-Philippe LafranceSameena Iqbal
Oct 20, 1998·The Journal of Hospital Infection·L A Herwaldt
Nov 19, 2008·Journal of Vascular Surgery·Frank T PadbergAnton N Sidawy
May 5, 2000·Seminars in Dialysis·Jerome I TokarsM Arduino
Aug 7, 2002·American Journal of Infection Control·Jerome I TokarsGary Stein

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