A prospective study of organochlorines in adipose tissue and risk of non‑Hodgkin lymphoma.

Environmental Health Perspectives
Elvira Vaclavik BräunerOle Raaschou-Nielsen

Abstract

Exposure to organochlorines has been examined as a potential risk factor for non-Hodgkin lymphoma (NHL), with inconsistent results that may be related to limited statistical power or to imprecise exposure measurements. Our purpose was to examine associations between organochlorine concentrations in prediagnostic adipose tissue samples and the risk of NHL. We conducted a case–cohort study using a prospective Danish cohort of 57,053 persons enrolled between 1993 and 1997. Within the cohort we identified 256 persons diagnosed with NHL in the population-based nationwide Danish Cancer Registry and randomly selected 256 subcohort persons. We measured concentrations of 8 pesticides and 10 polychlorinated biphenyl (PCB) congeners in adipose tissue collected upon enrollment. Associations between the 18 organochlorines and NHL were analyzed in Cox regression models, adjusting for body mass index. Incidence rate ratios and confidence intervals (CIs) for interquartile range increases in concentrations of dichlorodiphenyltrichlorethane (DDT), cis-nonachlor, and oxychlordane were 1.35 (95% CI: 1.10, 1.66), 1.13 (95% CI: 0.94, 1.36), and 1.11 (95% CI: 0.89, 1.38), respectively, with monotonic dose–response trends for DDT and cis-nonachlor bas...Continue Reading

References

Mar 1, 1971·Archives of Environmental Health·D P Morgan, C C Roan
Nov 14, 1997·Journal of Toxicology and Environmental Health·S L Archibeque-EngleT Zheng
May 7, 1997·Health Policy and Planning·R Repetto, S S Baliga
May 26, 1999·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·D N CoxD J Mela
Nov 15, 2000·Journal of Epidemiology and Community Health·P VineisA S Costantini
Mar 28, 2002·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·M F Allam, R A Lucena
Jun 11, 2002·Environmental Health Perspectives·Rosette L Van Den HeuvelGreet E R Schoeters
Nov 28, 2002·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·H TryphonasV Liston
Mar 4, 2003·Environmental Health Perspectives·Anders Wicklund GlynnElisabete Weiderpass
Aug 26, 2003·Occupational and Environmental Medicine·A J De RoosA Blair
Jun 4, 2004·Environmental Health Perspectives·Penelope J E QuintanaEric Garshick
Aug 24, 2004·Oncogene·Susan G Fisher, Richard I Fisher
Oct 30, 2004·American Journal of Physiology. Gastrointestinal and Liver Physiology·Ronald J JandacekPatrick Tso
Nov 24, 2004·Human & Experimental Toxicology·Adrian ReedMargaret M Whalen
Dec 8, 2004·Environmental Health Perspectives·Jay H LubinPatricia Hartge
Dec 8, 2004·Statistics in Medicine·Anne C M Thiébaut, Jacques Bénichou
Dec 3, 2005·Cancer Research·Anneclaire J De RoosNathaniel Rothman
Aug 24, 2006·Physiological Research·D Müllerová, J Kopecký
Oct 4, 2006·Acta Haematologica·Jacob Dreiher, Ella Kordysh
Mar 6, 2007·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Christine F Skibola
Aug 19, 2007·Occupational and Environmental Medicine·P CoccoP Boffetta
Aug 28, 2007·International Journal of Cancer. Journal International Du Cancer·John J SpinelliRichard P Gallagher
Jan 21, 2010·Epidemiology·Kimberly A BertrandFrancine Laden
Apr 22, 2010·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Francine LadenSharon K Sagiv
Feb 1, 2005·Environmental Toxicology and Pharmacology·Brian W WhitcombPaul J Kostyniak

❮ Previous
Next ❯

Citations

Apr 23, 2014·International Archives of Occupational and Environmental Health·Renate D KimbroughPeter G Shields
Oct 12, 2017·American Journal of Epidemiology·Christine G ParksDale P Sandler
May 16, 2013·Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews·Claudia ZaniFrancesco Donato
Oct 11, 2016·Archives of Toxicology·Sara Mostafalou, Mohammad Abdollahi
Feb 17, 2017·Environmental Health : a Global Access Science Source·Rachel S KellyUNKNOWN EnviroGenoMarkers project consortium
Sep 21, 2018·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Simona CatalaniPaolo Boffetta
Jun 19, 2013·Environmental Health Perspectives·Lifang HouMichael C Alavanja
Nov 22, 2012·Journal of Biochemical and Molecular Toxicology·Kristin M BircsakLauren M Aleksunes
Apr 28, 2017·Archives of Environmental Contamination and Toxicology·Stephanie A NormanStephen J Trumble
Jan 2, 2013·Cancer Causes & Control : CCC·Jun WangJoanne S Colt
Jan 17, 2013·CA: a Cancer Journal for Clinicians·Michael C R AlavanjaMatthew R Bonner
Nov 30, 2013·Bulletin of Experimental Biology and Medicine·N V YaglovaV V Yaglov
Jun 24, 2020·International Journal of Cancer. Journal International Du Cancer·Linda KachuriShelley A Harris
Dec 20, 2017·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Nina RoswallOle Raaschou-Nielsen
Oct 17, 2021·The Science of the Total Environment·Sara SousaValentina F Domingues

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy

Software Mentioned

SAS

Related Concepts

Related Feeds

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

B-Cell Lymphoma

B-cell lymphomas include lymphomas that affect B cells. This subtype of cancer accounts for over 80% of non-Hodgkin lymphomas in the US. Here is the latest research.

Related Papers

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology
Ole Raaschou-NielsenJørgen H Olsen
© 2022 Meta ULC. All rights reserved