A prospective study of quality of life among women undergoing risk-reducing salpingo-oophorectomy versus gynecologic screening for ovarian cancer.

Gynecologic Oncology
Carolyn Y FangMary B Daly

Abstract

The primary objective of the study was to prospectively assess quality of life (QOL) among women at increased risk of ovarian cancer who are undergoing risk-reducing salpingo-oophorectomy (RRSO) or serial screening. Women at increased risk of ovarian cancer who were undergoing RRSO were recruited into the study. At-risk women undergoing serial screening for early detection of ovarian cancer served as a comparison group. Participants completed measures of QOL, sexual functioning, body image, depressive symptoms, and a symptom checklist at baseline (prior to surgery for women obtaining RRSO), and then at 1-month, 6-months, and 12-months post baseline. Women who underwent surgery reported poorer physical functioning, more physical role limitations, greater pain, less vitality, poorer social functioning, and greater discomfort and less satisfaction with sexual activities at 1-month assessment compared to baseline. In contrast, women undergoing screening experienced no significant decrements in QOL or sexual functioning at 1-month assessment. Most QOL deficits observed in the surgical group were no longer apparent by 6-month assessment. Women in the surgery group were more likely to report hot flashes and vaginal dryness, but over t...Continue Reading

References

Feb 1, 1996·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·K ThirlawayJ Cuzick
May 25, 2002·The New England Journal of Medicine·Timothy R RebbeckUNKNOWN Prevention and Observation of Surgical End Points Study Group
Oct 29, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Patricia A GanzRebecca A Silliman
Nov 15, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Patricia A GanzJulienne E Bower
Mar 31, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Russell Hogg, Michael Friedlander
Apr 22, 2004·Gynecologic Oncology·Barry RosenUNKNOWN Cancer Care Ontario's Practice Guidelines Initiative Gynecology Cancer Disease Site Group
Nov 16, 2004·Menopause : the Journal of the North American Menopause Society·Alessandra Graziottin, Rosemary Basson
Aug 20, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Diane StirlingMary E Porteous
Sep 1, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Joanna B MadalinskaNeil K Aaronson
Mar 7, 2006·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·K N GaarenstroomG G Kenter
Jul 13, 2006·JAMA : the Journal of the American Medical Association·Amy FinchUNKNOWN Hereditary Ovarian Cancer Clinical Study Group
Sep 30, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·José G GuillemUNKNOWN SSO
Nov 11, 2006·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·P J C BresserA Tibben
Jan 24, 2007·The Breast : Official Journal of the European Society of Mastology·Penelope HopwoodUNKNOWN START Trial Management Group
Jul 31, 2007·Annals of Oncology : Official Journal of the European Society for Medical Oncology·P J C BresserA Tibben
Nov 16, 2007·Journal of Women's Health·Nancy K JanzSteven J Katz
Dec 8, 2007·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Kirsten B KluiversBen W J Mol
Feb 13, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Noah D KauffTimothy R Rebbeck
Apr 5, 2008·Health Care for Women International·M Tish Knobf

❮ Previous
Next ❯

Citations

Apr 3, 2014·Hereditary Cancer in Clinical Practice·Gillian W HookerMarc D Schwartz
Sep 11, 2010·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Suzanne M MillerJohn Scarpato
Nov 8, 2015·Gynecologic Oncology·Paige E TuckerPaul A Cohen
Aug 25, 2015·Critical Reviews in Oncology/hematology·Marline G HarmsenJoanne A de Hullu
Sep 1, 2015·Endocrinology and Metabolism Clinics of North America·Maria Rodriguez, Donna Shoupe
Apr 4, 2014·Journal of Psychosomatic Obstetrics and Gynaecology·Tierney LorenzElizabeth Swisher
Apr 20, 2016·Journal of Endocrinological Investigation·A Podfigurna-StopaB Meczekalski
Sep 8, 2009·Maturitas·Lynne T ShusterWalter A Rocca
Mar 11, 2017·Journal of Psychosomatic Obstetrics and Gynaecology·Marieke Arts-de JongJoanne A deHullu
Mar 24, 2017·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Paige E Tucker, Paul A Cohen
May 17, 2017·Climacteric : the Journal of the International Menopause Society·R F M VermeulenG G Kenter
Aug 24, 2013·Clinical Medicine Insights. Reproductive Health·Wendy MarderEmily C Somers
Jan 31, 2018·Menopause : the Journal of the North American Menopause Society·Tasneem SiyamNesé Yuksel
May 6, 2011·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Mark S CareyUNKNOWN Gynecologic Cancer InterGroup (GCIG)
Jul 29, 2016·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Paige E TuckerPaul A Cohen
Jan 26, 2016·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Ofer LavieYakir Segev
Jul 19, 2018·Menopause : the Journal of the North American Menopause Society·Jessica L ChanSusan M Domchek
Aug 13, 2011·Expert Review of Pharmacoeconomics & Outcomes Research·Dana M Chase, Lari Wenzel
May 14, 2019·Minerva medica·Angela TossGiovanni Grandi
Jan 7, 2018·Reproductive Health·Ranjan Kumar PrustyShiv Dutt Gupta
Oct 10, 2019·The Cochrane Database of Systematic Reviews·Lisa JeffersMartin Dempster
Oct 28, 2019·Psycho-oncology·C Bethan PowellTina Raine-Bennett
Feb 12, 2015·Obstetrical & Gynecological Survey·Christine Garcia, C Bethan Powell
Dec 17, 2014·Current Opinion in Obstetrics & Gynecology·Jocelyn S ChapmanLee-May Chen
Jan 18, 2018·The British Journal of Surgery·A M AltmanT M Tuttle
Dec 11, 2019·International Journal of Environmental Research and Public Health·Marta StaniszElżbieta Grochans
May 27, 2017·Breast Cancer Research and Treatment·Cara StabileJeanne Carter
Nov 4, 2017·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Anthony HowellD Gareth Evans

❮ Previous
Next ❯

Related Concepts

Related Feeds

Breast Cancer: BRCA1 & BRCA2

Mutations involving BRCA1, found on chromosome 17, and BRCA2, found on chromosome 13, increase the risk for specific cancers, such as breast cancer. Discover the last research on breast cancer BRCA1 and BRCA2 here.

Related Papers

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Joanna B MadalinskaNeil K Aaronson
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Joanna B MadalinskaNeil K Aaronson
Journal of the National Cancer Institute
Andrea EisenHereditary Breast Cancer Clinical Study Group
© 2021 Meta ULC. All rights reserved