A prospective study of the short-term quality of life outcomes of patients undergoing transperineal prostate biopsy

BJU International
Adam S DowrickDeclan G Murphy

Abstract

A prospective, observational study to investigate whether transperineal prostate biopsy (TPbx) results in patient-reported quality of life changes from baseline in the first three-months after the procedure. Consenting patients completed the Expanded Prostate cancer Index Composite (EPIC-26), the Sexual Health Inventory for Men (SHIM), the International Prostate Symptom Score (IPSS), the Generalised Anxiety Disorder (GAD-7), the Patient Health Questionnaire (PHQ-9) and a global question about willingness to have a repeat TPbx in a years' time. The instruments were scored using published scoring methods. Wilcoxon signed ranks tests and Mann-Whitney U tests were used to investigate statistically significant differences. Clinically significant differences were also investigated defined by published minimal important differences for the EPIC and changes in established categorical groups for the other instruments. Fifty-three participants consented to participate and completed the baseline questionnaire in addition to at least one of the 1- or 3-month follow-up questionnaires. We found that most patients having a TPbx had no clinically significant change in quality of life in the first three months following the procedure. However, ...Continue Reading

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Citations

Sep 16, 2016·International Journal of Clinical Oncology·Minoru KobayashiTakao Kamai
Mar 5, 2021·Investigative and Clinical Urology·Jo Lynn TanDaniel Moon

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