A prospective study on ultrasound-guided percutaneous thrombin injection for treatment of iatrogenic post-catheterisation femoral pseudoaneurysms

International Journal of Cardiology
Carsten SchneiderKarl-Heinz Kuck

Abstract

The purpose of this study was to evaluate prospectively the safety and efficacy of bovine thrombin injection for the treatment of iatrogenic post-catheterisation pseudoaneurysms. A total of 274 patients (90 women, 184 men, 69.8+/-7 years) with iatrogenic femoral pseudoaneurysms were treated by ultrasound-guided thrombin injection (UGTI). The deepest pseudoaneurysm chamber was entered with a 0.90x40 mm or 90 mm needle and bovine thrombin (solution of 1000 U/ml) was injected. Pseudoaneurysms were associated with diagnostic cardiac catheterisation, percutaneous coronary intervention or invasive electrophysiologic investigation. The majority of the patients were under antiplatelet therapy with aspirin or clopidogrel or both, and additional low dose heparin therapy. A total of 52 patients were treated with either phenprocoumon or enoxaparine body weight adjusted. UGTI was primary successful in 267 of 274 patients (97%). In 3 of 7 patients with a remaining pseudoaneurysm a second injection was required. Three patients were treated by ultrasound-guided compression. One patient was treated by surgical repair of the pseudoaneurysm 1 day after UGTI because a further pseudoaneurysm developed under phenprocoumon therapy. UGTI-related compl...Continue Reading

References

Aug 1, 1986·AJR. American Journal of Roentgenology·C Cope, R Zeit
May 1, 1997·Journal of Vascular Surgery·B ToursarkissianG A Sicard
May 13, 1999·The British Journal of Radiology·H W Loose, P J Haslam
Mar 17, 2000·Investigative Radiology·H J SteinkampR Felix
May 8, 2001·Journal of Vascular and Interventional Radiology : JVIR·S Sadiq, W Ibrahim
Dec 26, 2001·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·E E WeinmannA Bass
Mar 20, 2002·Cardiovascular and Interventional Radiology·Julian ElfordCarl Roobottom
Apr 18, 2002·Vascular Medicine·E R MohlerM Gerhard-Herman
Mar 26, 2003·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Günter Görge, Thomas Kunz
Apr 28, 2005·AJR. American Journal of Roentgenology·Victoria VázquezPascual Parrilla
Jan 21, 2006·AJR. American Journal of Roentgenology·Anil K DasyamSharlene A Teefey
Apr 7, 2006·Vascular and Endovascular Surgery·Patrick A StoneMark C Bates

❮ Previous
Next ❯

Citations

Sep 17, 2009·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Juraj MadaricJozef Bartunek
Dec 25, 2013·Annals of Vascular Surgery·Pamela C MasellaDwight C Kellicut
Nov 19, 2011·International Journal of Surgery Case Reports·C N ParnabyJ G Docherty
Mar 24, 2015·Circulation Journal : Official Journal of the Japanese Circulation Society·Sosei KumaShinsuke Mii
Mar 26, 2016·Journal of Vascular and Interventional Radiology : JVIR·Jason J BoubalosDimitri A Parra
Jul 3, 2016·Vascular·Farah MohammadAlexander Shepard
Apr 14, 2017·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Yonah B Esterson, John S Pellerito
Jun 26, 2017·Annals of Vascular Surgery·Nandakumar MenonShahab Toursavadkohi
Sep 13, 2012·Vascular and Endovascular Surgery·Patrick A Stone, John E Campbell
Aug 10, 2013·Vascular·Irene ThomassenJoep A W Teijink
Feb 15, 2018·VASA. Zeitschrift für Gefässkrankheiten·Maria StoltJoerg Herold
Apr 23, 2019·The Journal of International Medical Research·Chi-Chang LiZhi-Peng Zheng
May 23, 2014·Expert Review of Cardiovascular Therapy·Giuseppe VergaroAndrea Del Corso
May 17, 2019·JAAPA : Official Journal of the American Academy of Physician Assistants·Carol Madia
Jun 20, 2020·Vascular and Endovascular Surgery·Maria GummererHannes Gruber
Sep 28, 2018·Hämostaseologie·Sophie PetersJoerg Herold
Apr 16, 2019·The British Journal of Radiology·Jonathan DelfNeghal Kandiyil
Apr 2, 2018·Journal of Ultrasound·Ashraf Talaat Youssef
Apr 19, 2021·Indian Heart Journal·Keshavamurthy Ganapathy BhatAmitoj Singh Chadha
May 4, 2021·VASA. Zeitschrift für Gefässkrankheiten·Christos Rammos, Tienush Rassaf
Feb 6, 2020·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·Jacek KurzawskiMarcin Sadowski
Sep 4, 2019·Archives of Medical Science : AMS·Froylan Albarrán-TamayoSergio López Briones

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.