PMID: 9165382Apr 1, 1997Paper

A prospective test of criteria for response, remission, relapse, recovery, and recurrence in depressed patients treated with cognitive behavior therapy

Journal of Affective Disorders
L P RisoX M Tu

Abstract

The definitions that are commonly employed to describe the outcome of the depressive disorders are often used in inconsistent ways and remain largely untested. The lack of a standard and valid set of outcome definitions hinders the study of the naturalistic course and treatment of depressive disorders. In the present study, we operationalized definitions for response, remission, relapse, recovery, and recurrence and examined their validity in a sample of depressed patients treated with cognitive behavior therapy. Validity was evaluated by the ability of the definitions to predict subsequent outcome in acute treatment and during a 3 year follow-up period. All five definitions demonstrated moderate to excellent validity. Moreover, we were able to empirically distinguish response from remission, and relapse from recurrence, despite the frequent confusion of these terms in the literature. Several of the findings suggest that continued refinement of the outcome definitions may enhance validity even further.

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Citations

Apr 5, 2005·Depression and Anxiety·Helen Blair SimpsonMichael R Liebowitz
Apr 6, 2004·Controlled Clinical Trials·A John RushUNKNOWN STAR*D Investigators Group
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May 8, 2010·Journal of Psychiatric Research·Michael RiedelFlorian Seemüller
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Apr 24, 2021·Clinical Psychopharmacology and Neuroscience : the Official Scientific Journal of the Korean College of Neuropsychopharmacology·Cheolmin ShinChangsu Han

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