A prospective trial for laparoscopic adjustable gastric banding in morbidly obese adolescents: an interim report of weight loss, metabolic and quality of life outcomes

Journal of Pediatric Surgery
Ai-Xuan HoltermanMark J Holterman

Abstract

BACKGROUND AND MATERIALS AND METHODS: The outcome of patients completing 12 months of follow-up in a prospective longitudinal trial of the safety/efficacy of laparoscopic adjustable gastric banding (LAGB) for morbidly obese adolescents aged 14 to 17 years using a Food and Drug Administration Institutional Device Exemption for the use of the LAPBAND was analyzed. Baseline and outcome data were abstracted from a prospective database. Baseline (mean +/- SD) body mass index was 50 +/- 10 kg/m(2), and excess weight was 178 +/- 53 lb in 20 patients. Comorbidities included hypertension (45%), dyslipidemia (80%), insulin resistance (90%), metabolic syndrome (95%), and biopsy-proven nonalcoholic steatohepatitis (88%). At mean (SD) follow-up of 26 (9) months, % excess weight loss was 34% +/- 22% (n = 20) and 41% +/- 27% (n = 12), and the metabolic syndrome was resolved in 63% and 82% of the patients at 12 and 18 months, respectively. Hypertension normalized in all patients, along with improvement in lipid abnormalities and quality of life scores (P < .05). At 12 months, of the 5 patients with less than 20% excess weight loss, dyslipidemia and metabolic syndrome were resolved in 2 patients. At intermediate follow-up of a LAGB-based obesit...Continue Reading

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Citations

Oct 14, 2011·Surgical Endoscopy·Raghavendra S Rao, Subhash Kini
Mar 12, 2013·Current Hypertension Reports·Susan M Halbach, Joseph Flynn
Sep 21, 2013·International Journal of Obesity : Journal of the International Association for the Study of Obesity·B S LennerzC Stroh
Feb 5, 2014·Seminars in Pediatric Surgery·AiXuan HoltermanNerina DiSomma
Feb 5, 2014·Seminars in Pediatric Surgery·Jeffrey L Zitsman
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Jan 18, 2011·Journal of Pediatric Surgery·Jeffrey L ZitsmanMarc Bessler
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Apr 18, 2013·Obesity·Ai-Xuan L HoltermanMark Holterman
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