A prospective trial of elective preterm delivery for fetal gastroschisis

American Journal of Perinatology
Christopher R MoirKirk D Ramin

Abstract

To test the hypothesis that preterm delivery of fetal gastroschisis prevents serious gastrointestinal compromise, facilitates primary surgical closure, and improves surgical outcome, we enrolled 16 women in a management plan. This included high-resolution ultrasound, weekly re-evaluation of the fetal gut (> or = 26 weeks), corticosteroids, and delivery if evidence of bowel compromise was present > 30 weeks. These fetuses were compared with 16 consecutive patients treated prior to establishment of this plan. Comparison of prospective trial patients with controls revealed significant differences in age at delivery (34.2 versus 37.7 weeks), serious bowel compromise (0 versus 70%), use of a surgically constructed silo (0 versus 77%), wound complications (0 versus 23%), duration of total parenteral nutrition (18.7 versus 34.7 days), time to full enteral feeding (19.1 versus 35.1 days), and hospital discharge (22.7 versus 37.7 days). Elective preterm delivery using specific ultrasound criteria resulted in improved surgical outcome without significant morbidity secondary to prematurity.

Citations

Mar 16, 2007·Pediatric Surgery International·Kokila Lakhoo
Jun 20, 2007·Pediatric Surgery International·L Cara Jager, Hugo A Heij
Aug 19, 2007·Pediatric Surgery International·F L MurphyP Puri
Aug 1, 2008·Pediatric Surgery International·Thomas GelasRémi Dubois
Aug 6, 2010·Pediatric Surgery International·Andrew J A HollandNadia Badawi
Dec 17, 2010·Pediatric Surgery International·Vincent E MortellaroSaleem Islam
Jun 5, 2012·Archives of Gynecology and Obstetrics·Karine BarseghyanDavid A Miller
May 20, 2008·Maternal and Child Health Journal·Margaret A HoneinUNKNOWN National Birth Defects Prevention Network
Feb 19, 1999·Journal of the American College of Surgeons·B M Rodgers
Mar 11, 2005·Current Opinion in Obstetrics & Gynecology·Göran Lingman
May 14, 2008·Current Opinion in Pediatrics·Saleem Islam
Dec 3, 2014·Seminars in Pediatric Surgery·Piergiorgio Gamba, Paola Midrio
Jun 22, 2007·Journal de gynécologie, obstétrique et biologie de la reproduction·X CapelleJ-M Foidart
Sep 15, 2009·Early Human Development·Nigel J HallAgostino Pierro
Jul 4, 2009·Journal of Pediatric Surgery·Hima MaramreddyBoriana Parvez
Feb 24, 2009·Journal of Pediatric Surgery·Chris HoubenShailesh Patel
Nov 21, 2008·Seminars in Pediatric Surgery·Sean Marven, Anthony Owen
Apr 4, 2006·The Surgical Clinics of North America·Daniel J Ledbetter
Jul 26, 2008·American Journal of Medical Genetics. Part C, Seminars in Medical Genetics·Peter F NicholYukio Saijoh
Jan 14, 2010·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·E ControA Bhide
Dec 11, 2007·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Titia E Cohen-OverbeekDick Tibboel
May 9, 2006·Journal of Pediatric Surgery·Hannah G Piper, Tom Jaksic
Mar 28, 2006·Early Human Development·Melanie DrewettDavid Burge
May 16, 2007·Journal of Pediatric Surgery·Paul CharlesworthMark Davenport
Nov 8, 2014·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·L M HarperG A Macones
May 1, 2013·American Journal of Obstetrics and Gynecology·Andrew P SouthJareen Meinzen-Derr
Dec 7, 2011·Early Human Development·Kokila Lakhoo
Nov 12, 2013·Journal of Pediatric Surgery·Ahmed NasrUNKNOWN Canadian Pediatric Surgery Network
Jun 4, 2014·Journal of Pediatric Surgery·Helen CarnaghanSimon Eaton
Jun 10, 2016·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Tiphaine Raia-BarjatFrançois Varlet
Oct 21, 2016·American Journal of Obstetrics and Gynecology·Teresa N SparksAaron B Caughey
Mar 25, 2017·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Vito BrigantiFabrizio Signore
Aug 28, 2014·Obstetrics and Gynecology·Mary Ashley CainHamisu M Salihu
Jul 21, 2012·Fetal Diagnosis and Therapy·Megan S WilsonKelly A Bennett
May 3, 2013·Obstetrics and Gynecology·David BaudGreg Ryan
Sep 11, 2019·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A A ShamshirsazM A Belfort
Oct 16, 2019·Journal of Paediatrics and Child Health·Jeremy GrangerCatherine L Cord-Udy
Jul 23, 2016·Khirurgiia·Yu A KozlovN N Kuznetsova
Sep 27, 2018·Pediatric Surgery International·Richard H PearlCharles J Aprahamian
Mar 8, 2020·Journal of Neonatal-perinatal Medicine·Shilpi ChabraEdith Y Cheng
Sep 2, 2019·Journal of Pediatric Surgery·Russell B HawkinsSaleem Islam
Apr 14, 2005·Prenatal Diagnosis
Sep 28, 2017·Journal of Pediatric Surgery·Rachel M LandischAmy J Wagner

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
R P JaparajF Y Chan
Journal of Pediatric Surgery
J BaergD Reid
© 2022 Meta ULC. All rights reserved