PMID: 5259771Jul 1, 1969Paper

A protein intermediary in the interaction of a hormone with the genome

Proceedings of the National Academy of Sciences of the United States of America
A G Matthysse, C Phillips

Abstract

The increased rate of RNA synthesis by target cells caused by the plant hormone auxin has been studied as an example of hormonal regulation of transcription. The hormone does not interact directly with chromatin but requires a protein mediator. In the presence of this mediator, auxin increases the rate of RNA synthesis both by isolated plant nuclei and by isolated chromatin. This increased rate of RNA synthesis occurs even in the presence of saturating amounts of RNA polymerase. The hormone and protein do not affect the rate of RNA synthesis if pure DNA is used as the template. The results suggest that auxin plus the protein increase the rate of RNA synthesis by making an increased portion of the genome available for transcription.

References

Nov 1, 1965·Proceedings of the National Academy of Sciences of the United States of America·M E Dahmus, J Bonner
Jun 1, 1966·Proceedings of the National Academy of Sciences of the United States of America·D Toft, J Gorski
Oct 1, 1966·Proceedings of the National Academy of Sciences of the United States of America·K L Barker, J C Warren
Jan 1, 1968·Proceedings of the National Academy of Sciences of the United States of America·M M Johri, J E Varner
Apr 1, 1969·Biochemistry·M E Dahmus, D J McConnell
Aug 1, 1965·Experimental Cell Research·P Filner
Jan 1, 1966·Journal of Molecular Biology·K Marushige, J Bonner
Jul 15, 1962·Proceedings of the National Academy of Sciences of the United States of America·R C HUANG, J BONNER

❮ Previous
Next ❯

Citations

Jan 1, 1976·Planta·R KonjevićJ Petrović
Apr 1, 1970·Proceedings of the National Academy of Sciences of the United States of America·C R Morgan, J Bonner
Aug 1, 1971·Proceedings of the National Academy of Sciences of the United States of America·M A Venis
Nov 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·J W HardinC A Lembi
Jun 1, 1975·Plant Physiology·N J Leonard, J C Greenfield
Jul 1, 1975·Plant Physiology·E M Tobin, A O Klein
Nov 16, 1972·Biochimica Et Biophysica Acta·T V Gopalakrishnan, A Sadgopal
Feb 18, 1970·Biochimica Et Biophysica Acta·A G Matthysse, M Abrams
Feb 18, 1970·Biochimica Et Biophysica Acta·A G Matthysse
Dec 14, 1970·Biochimica Et Biophysica Acta·J W HardinJ H Cherry
Feb 21, 1977·Biochemical and Biophysical Research Communications·P Roy, B B Biswas
Sep 1, 1970·Experimental Cell Research·T H SchieblerC Pilgrim
Apr 14, 1972·Biochemical and Biophysical Research Communications·D Salomon, J P Mascarenhas
Mar 27, 1970·Biochemical and Biophysical Research Communications·A A Khan, C C Anojulu
Nov 22, 1972·Nature: New Biology·H MondalB B Biswas
Jun 15, 1979·FEBS Letters·S R ChungB Durand
Oct 7, 1976·Differentiation; Research in Biological Diversity·E C Schmidt, R M Goodman

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved