A pulsatile control algorithm of continuous-flow pump for heart recovery

ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs
Bin GaoYoujun Liu

Abstract

The intra-aorta pump is a novel continuous flow (CF) left ventricular (LV) device. According to literatures, the pulsatile flow LV device can provide superior LV unloading and circulatory support compared with CF LV assist devices at the same level of ventricular assist device flow. Therefore, a pulsatile control algorithm for the intra-aorta pump is designed. It can regulate the pump to generate pulsatile arterial pressure (AP) and blood flow. A mathematic model of the cardiovascular-pump system is used to verify the feasibility of the control strategy in the presence of LV failure. The surplus hemodynamic energy (SHE), pulsatile ratio (PR), and pulsatile attenuation index (PAI) are used to evaluate the pulsatility of AP and blood flow. The SHE is 8,012.0 ergs/cm(3) by using the pulsatile control strategy (PCS) compared with 5,630.0 ergs/cm(3) by failing heart without support. The PR is 0.302 in the PCS vs. 0.315 in failing heart without support. Meanwhile, the PAI is 85.9% in the PCS compared with 69.7% in failing heart without support. The results demonstrate that the presented control strategy can maintain the pulsatility of AP and blood flow. Moreover, the pulsatile controller provides notably LV unloading. To test the res...Continue Reading

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Jul 8, 2011·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Bin GaoYu Chang

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Citations

May 6, 2014·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Zhiming SongYi Zeng
Sep 27, 2015·Computers in Biology and Medicine·Yi Wu, Qing Zheng
Mar 13, 2014·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Feng HuangXin Fu
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Jul 22, 2016·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Qi ZhangYu Chang
Nov 11, 2019·Medical & Biological Engineering & Computing·Bin GaoYu Chang

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