A pulse sequence for rapid in vivo spin-locked MRI

Journal of Magnetic Resonance Imaging : JMRI
Arijitt BorthakurRavinder Reddy

Abstract

To develop a novel pulse sequence called spin-locked echo planar imaging (EPI), or (SLEPI), to perform rapid T1rho-weighted MRI. SLEPI images were used to calculate T1rho maps in two healthy volunteers imaged on a 1.5-T Sonata Siemens MRI scanner. The head and extremity coils were used for imaging the brain and blood in the popliteal artery, respectively. SLEPI-measured T1rho was 83 msec and 103 msec in white (WM) and gray matter (GM), respectively, 584 msec in cerebrospinal fluid (CSF), and was similar to values obtained with the less time-efficient sequence based on a turbo spin-echo readout. T1rho was 183 msec in arterial blood at a spin-lock (SL) amplitude of 500 Hz. We demonstrate the feasibility of the SLEPI pulse sequence to perform rapid T1rho MRI. The sequence produced images of higher quality than a gradient-echo EPI sequence for the same contrast evolution times. We also discuss applications and limitations of the pulse sequence.

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May 27, 2003·Journal of Magnetic Resonance Imaging : JMRI·Arijitt BorthakurRavinder Reddy
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Apr 6, 2004·Journal of Magnetic Resonance Imaging : JMRI·Arijitt BorthakurRavinder Reddy

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Citations

Aug 6, 2014·Magnetic Resonance Imaging·Casey P JohnsonVincent A Magnotta
May 23, 2014·Magnetic Resonance Imaging·Swati RaneJohn C Gore
Aug 13, 2009·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Walter R T WitscheyRavinder Reddy
Sep 9, 2008·Journal of Magnetic Resonance Imaging : JMRI·Walter R T WitscheyRavinder Reddy
Jun 18, 2014·Journal of Magnetic Resonance Imaging : JMRI·Ligong Wang, Ravinder R Regatte
Apr 5, 2014·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Qi LiuDebiao Li
Jan 30, 2014·Journal of Magnetic Resonance Imaging : JMRI·Casey P JohnsonVincent A Magnotta
Apr 22, 2016·NMR in Biomedicine·Irtiza Ali Gilani, Raimo Sepponen
Jan 30, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Xiaojuan LiSharmila Majumdar
Jan 18, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Trong-Kha TruongAllen W Song
Nov 17, 2020·Frontiers in Psychiatry·Joseph J ShafferJohn A Wemmie
May 31, 2021·Magnetic Resonance Imaging·Fatemeh AdelniaJohn C Gore

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