A putative RNA-binding protein has a role in virulence in Ralstonia solanacearum GMI1000.

Molecular Plant Pathology
Ashley FranksFergal O'Gara

Abstract

Molecular signals contained in root exudates are thought to induce specific transcriptional changes in bacteria within the rhizosphere, promoting the expression of genes associated with rhizosphere function. We have previously used Pseudomonas aeruginosa PAO1 as a model organism to identify novel genes with roles in rhizosphere competitiveness through analysis of those which showed altered transcription in response to root exudates. One such gene, PA4753, encodes a putative RNA-binding protein. Homologues of PA4753 occur in other rhizosphere-associated bacteria, including the phytopathogen Ralstonia solanacearum. In this study, we have tested the role of this homologue, Rsc1524, in the virulence of R. solanacearum GMI1000. Disruption of Rsc1524 resulted in a decrease in virulence in tomato and Arabidopsis. This was associated with an increase in the level of specific extracellular plant wall-degrading enzymes. Expression of Rsc1524 was influenced by different plant root exudates and root exudate components, which suggests that it may play a role in molecular signalling between bacteria and plants underpinning wilt pathogenesis.

References

Mar 1, 1992·Journal of Bacteriology·Z M WeiS V Beer
Mar 1, 1992·Molecular Plant-microbe Interactions : MPMI·M ArlatC A Boucher
Sep 1, 1996·Molecular Plant-microbe Interactions : MPMI·M SimonsB J Lugtenberg
Jun 11, 1999·Molecular Microbiology·V Oke, S R Long
Apr 12, 2000·Proceedings of the National Academy of Sciences of the United States of America·M H Rashid, A Kornberg
Feb 24, 2001·Environmental Microbiology·B J Lugtenberg, L C Dekkers
May 24, 2001·Journal of Bacteriology·J Tans-KerstenC Allen
Nov 10, 2001·Annual Review of Phytopathology·B J LugtenbergG V Bloemberg
Feb 2, 2002·Nature·M SalanoubatC A Boucher
Jun 11, 2003·Molecular Plant-microbe Interactions : MPMI·Enid T González, Caitilyn Allen
Jun 16, 2004·Molecular Plant-microbe Interactions : MPMI·Julie Tans-KerstenCaitilyn Allen
Sep 3, 2004·Molecular Microbiology·Darby G Brown, Caitilyn Allen
Nov 23, 2005·Proceedings of the National Academy of Sciences of the United States of America·G Louise MarkFergal O'Gara
May 1, 2002·Molecular Plant Pathology·Stéphane Genin, Christian Boucher

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.