PMID: 3750868Jan 1, 1986Paper

A qualitative and quantitative analysis of the human fovea during development

Vision Research
C Yuodelis, A Hendrickson

Abstract

The anatomical development of the human fovea has been sampled from 22 weeks gestation to adulthood, using both qualitative and quantitative methods. The foveal depression continues to deepen after birth until 15 months, due to the migration of the cells of the inner retina toward the periphery. Before birth the rod-free zone or foveola is over 1000 microns in diameter, but it becomes progressively narrower after birth because of a centralward migration of cones. It reaches the adult diameter of 650-700 microns by 45 months of age. Postnatally, foveolar cone development is characterized by maturation, elongation, and an increase in packing density. Foveolar cone diameter changes markedly after birth, going from 7.5 microns at 5 days postnatal to 2 microns by 45 months. During this time the foveolar cone develops both its outer segment and basal axon process (fiber of Henle). This combination of elongation and centralward migration results in an increase of foveolar cone density from 18 cones/100 microns at 1 week postnatal to 42 cones/100 microns in the adult. Measures of foveola width and cone diameter reach the adult stage of development at 45 months of age, but the two important visual factors of outer segment length and con...Continue Reading

References

Jan 1, 1985·Annual Review of Neuroscience·R G BootheD Y Teller
Aug 1, 1969·Archives of Ophthalmology·E Yamada
Aug 1, 1973·The American Journal of Anatomy·M J Hollenberg, A W Spira
Aug 1, 1965·Journal of Ultrastructure Research·O Trujillo-Cenóz
Jul 16, 1982·Science·I AbramovE LaBossiere
Jun 1, 1984·Ophthalmology·A E Hendrickson, C Yuodelis
Mar 1, 1981·Survey of Ophthalmology·A B FultonK A Manning
Jul 1, 1980·American Journal of Optometry and Physiological Optics·J GwiazdaR Held

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Citations

Jan 1, 1995·Documenta Ophthalmologica. Advances in Ophthalmology·M B MetsA Pass
Jan 1, 1994·Documenta Ophthalmologica. Advances in Ophthalmology·I Geer, M M Spafford
Aug 31, 2012·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·E R Tamm, A Ohlmann
May 3, 2013·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Yong Un ShinByung Ro Lee
Feb 28, 2006·Documenta Ophthalmologica. Advances in Ophthalmology·Anne B FultonAmber M Barnaby
Feb 1, 2008·Documenta Ophthalmologica. Advances in Ophthalmology·Eva LenassiJelka Brecelj
Sep 9, 2008·Documenta Ophthalmologica. Advances in Ophthalmology·C PiehM Bach
Feb 20, 2013·Documenta Ophthalmologica. Advances in Ophthalmology·Alice D McTrustyGraeme J Kennedy
Jan 1, 1988·Vision Research·H R WilsonA B Kressel
Jan 1, 1988·Vision Research·D S Jacobs, C Blakemore
Jan 1, 1988·Vision Research·H R Wilson
Jan 1, 1989·Vision Research·J Hirsch, C A Curcio
Jan 1, 1990·Vision Research·S L Shea, R N Aslin
Oct 1, 1992·Vision Research·R E Manny
Oct 1, 1992·Vision Research·P OssenblokH Spekreijse
Nov 1, 1992·Vision Research·D AllenM S Banks
Aug 1, 1992·Vision Research·J ZankerM Fahle
Jul 1, 1994·Vision Research·R J AdamsM E Mercer
Mar 1, 1994·Vision Research·P S SuterJ C Powers
Sep 1, 1994·Vision Research·R D Hamer, A M Norcia
Aug 20, 1993·Brain Research. Developmental Brain Research·T C Steineke, M A Kirby
Mar 8, 2003·Ophthalmology·Ann H MilamSamuel G Jacobson
Apr 29, 1998·Progress in Neurobiology·J M ProvisB Dreher
Oct 6, 2001·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·D A Dunn, J L Johnson
Apr 5, 2001·Progress in Retinal and Eye Research·P L PenfoldJ M Provis
Oct 6, 2001·Progress in Retinal and Eye Research·J M Provis
Jan 27, 1999·Progress in Retinal and Eye Research·R GuymerA Bird
Nov 6, 2002·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Jelka BreceljM Tekavcic-Pompe
Jan 1, 1992·Visual Neuroscience·D C Coile, H D Baker

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