A quality assurance method that utilizes 3D dosimetry and facilitates clinical interpretation.

International Journal of Radiation Oncology, Biology, Physics
Mark OldhamJohn P Kirkpatrick

Abstract

To demonstrate a new three-dimensional (3D) quality assurance (QA) method that provides comprehensive dosimetry verification and facilitates evaluation of the clinical significance of QA data acquired in a phantom. Also to apply the method to investigate the dosimetric efficacy of base-of-skull (BOS) intensity-modulated radiotherapy (IMRT) treatment. Two types of IMRT QA verification plans were created for 6 patients who received BOS IMRT. The first plan enabled conventional 2D planar IMRT QA using the Varian portal dosimetry system. The second plan enabled 3D verification using an anthropomorphic head phantom. In the latter, the 3D dose distribution was measured using the DLOS/Presage dosimetry system (DLOS = Duke Large-field-of-view Optical-CT System, Presage Heuris Pharma, Skillman, NJ), which yielded isotropic 2-mm data throughout the treated volume. In a novel step, measured 3D dose distributions were transformed back to the patient's CT to enable calculation of dose-volume histograms (DVH) and dose overlays. Measured and planned patient DVHs were compared to investigate clinical significance. Close agreement between measured and calculated dose distributions was observed for all 6 cases. For gamma criteria of 3%, 2 mm, th...Continue Reading

References

May 30, 2003·Medical Physics·Joseph O DeasyVanessa H Clark
Apr 27, 2007·Journal of Physics. Conference Series·Mark Oldham
Aug 23, 2007·Journal of Applied Clinical Medical Physics·Benjamin E Nelms, Jeff A Simon
Feb 25, 2009·Medical Physics·H S SakhalkarM Oldham
Mar 5, 2010·International Journal of Radiation Oncology, Biology, Physics·Yaacov Richard LawrenceAdam P Dicker
Apr 28, 2011·Medical Physics·Daniel A LowMark Oldham
Jul 2, 2011·Physics in Medicine and Biology·Andrew ThomasMark Oldham
Sep 21, 2011·Medical Physics·Andrew ThomasMark Oldham

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Citations

May 3, 2013·Medical Physics·Leith Rankine, Mark Oldham
Feb 11, 2014·Medical Physics·Kiley B PulliamStephen F Kry
Aug 10, 2013·Medical Physics·Yoichi Watanabe, Yuji Nakaguchi
Jul 6, 2014·Medical Physics·Titania JuangMark Oldham
Jun 10, 2014·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Kieyin TengMoshi Geso
Jul 28, 2013·International Journal of Radiation Oncology, Biology, Physics·Titania JuangMark Oldham
Apr 1, 2015·Practical Radiation Oncology·Michael VelecKristy K Brock
Jan 24, 2020·Medical Physics·Christian VeltenCheng-Shie Wuu
Nov 23, 2013·Physics in Medicine and Biology·Xin QianCheng-Shie Wuu
Feb 17, 2015·Physics in Medicine and Biology·Jake JacksonMark Oldham
Jun 10, 2015·Physics in Medicine and Biology·Carl StanhopeJustus Adamson
Feb 20, 2016·Journal of Applied Clinical Medical Physics·Drew McVickerJustus D Adamson
Jun 25, 2014·Physics in Medicine and Biology·A K VidovicM Oldham
Apr 2, 2021·Journal of Applied Clinical Medical Physics·Yi-Fang WangCheng-Shie Wuu
Apr 24, 2021·Dose-response : a Publication of International Hormesis Society·Yiling WangJinyi Lang

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