A quantitative exploration of gastrointestinal bleeding in intensive care unit patients

PloS One
Patrick C Eschenfeldt, Chin Hur

Abstract

Quantitative assessments of the severity of bleeding in patients with bleeds within the gastrointestinal tract (GIB) are generally limited to blood tests like the hematocrit. The varied and irregular nature of the data collected during such observations makes it difficult in retrospective data analysis to characterize the complete course of bleeding. We intend to quantify the rate of blood loss over the course of an ICU stay, facilitating more precise analysis of retrospective data, and to use this quantification to examine questions about the effects of GIB. A population of 2,445 intensive care admissions across 2,266 patients with a diagnosis of GIB was studied. Using statistical techniques for smoothing data and accepted medical approaches for calculating blood loss, we are able to convert collections of individual laboratory readings that are difficult to understand into a simple, interpretable overview of the patient's bleeding status over time. To demonstrate this method, we compare patients' standard vital signs while bleeding heavily to times when they are not bleeding, finding a 3.0 ± 0.5% increase in heart rate, a 1.3 ± 0.4% decrease in systolic blood pressure and a 0.9 ± 0.5% decrease in diastolic blood pressure. Aft...Continue Reading

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May 25, 2016·Scientific Data·Alistair E W JohnsonRoger G Mark

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Citations

Nov 18, 2020·Scandinavian Journal of Gastroenterology·Minoru FujitaKen Haruma

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Software Mentioned

Python
SciPy

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