A quantitative study of IMRT delivery effects in commercial planning systems for the case of oesophagus and prostate tumours

The British Journal of Radiology
J SecoS Webb

Abstract

This study focuses on understanding the impact of intensity-modulated radiotherapy (IMRT) delivery effects when applied to plans generated by commercial treatment-planning systems such as Pinnacle (ADAC Laboratories Inc.) and CadPlan/Helios (Varian Medical Systems). These commercial planning systems have had several version upgrades (with improvements in the optimization algorithm), but the IMRT delivery effects have not been incorporated into the optimization process. IMRT delivery effects include head-scatter fluence from IMRT fields, transmission through leaves and the effect of the rounded shape of the leaf ends. They are usually accounted for after optimization when leaf sequencing the "optimal" fluence profiles, to derive the delivered fluence profile. The study was divided into two main parts: (a) analysing the dose distribution within the planning-target volume (PTV), produced by each of the commercial treatment-planning systems, after the delivered fluence had been renormalized to deliver the correct dose to the PTV; and (b) studying the impact of the IMRT delivery technique on the surrounding critical organs such as the spinal cord, lungs, rectum, bladder etc. The study was performed for tumours of (i) the oesophagus ...Continue Reading

References

May 15, 1991·International Journal of Radiation Oncology, Biology, Physics·B EmamiM Wesson
Feb 1, 1994·International Journal of Radiation Oncology, Biology, Physics·M K MartelA S Lichter
Jul 31, 1998·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·M K MartelA S Lichter
Jul 6, 2001·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·M EssersB J Heijmen
Jul 28, 2001·Physics in Medicine and Biology·W BärF Nüsslin
Aug 17, 2002·International Journal of Radiation Oncology, Biology, Physics·Linda HongSteve Leibel
Oct 18, 2002·Journal of Applied Clinical Medical Physics·C H ClarkD P Dearnaley
Mar 19, 2004·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Catharine H ClarkChristopher M Nutting

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Citations

Sep 8, 2007·Medical Physics·Jeffrey V SiebersV Ramakrishnan
Mar 19, 2014·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Conor K McGarryAlan R Hounsell
Sep 9, 2015·Physics in Medicine and Biology·Yang ShengQ Jackie Wu

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