A quasi-experimental analysis of maternal altitude exposure and infant birth weight

American Journal of Public Health
Sammy ZahranStephan Weiler

Abstract

We analyzed singleton births to determine the relationship between birth weight and altitude exposure. We analyzed 715,213 singleton births across 74 counties from the western states of Arizona, California, Colorado, Idaho, Montana, Nevada, New Mexico, Oregon, Utah, and Washington from January 1, 2000, to December 31, 2000. Birth data were obtained from the Division of Vital Statistics, National Center for Health Statistics, for registered births. Regression analyses supported previous research by showing that a 1000-meter increase in maternal altitude exposure in pregnancy was associated with a 75.9-gram reduction in birth weight (95% confidence interval = -84.1, -67.6). Quantile regression models indicated significant and near-uniform depressant effects from altitude exposure across the conditional distribution of birth weight. Bivariate sample-selection models showed that a 1000-meter increase in altitude exposure, over and above baseline residential altitude, decreased birth weight by an additional 58.8 grams (95% confidence interval = -98.4, -19.2). Because of calculable health care-related costs associated with lower birth weight, our reported results might be of interest to clinicians practicing at higher altitudes.

References

Jun 17, 1988·JAMA : the Journal of the American Medical Association·C UngerL G Moore
Dec 1, 1987·The Journal of Pediatrics·R Yip
Jun 1, 1997·American Journal of Public Health·G M Jensen, L G Moore
May 18, 1999·American Journal of Obstetrics and Gynecology·S K PalmerStacy Zamudio
Mar 4, 2000·The Journal of Pediatrics·J P MortolaK Armstrong
Mar 27, 2001·Pediatric Research·Dino A GiussaniD J Barker
Jun 1, 1957·A.M.A. Journal of Diseases of Children·J A LICHTYE DYAR
Jun 1, 1957·A.M.A. Journal of Diseases of Children·R C HOWARDP D BRUNS
May 11, 2005·Maternal and Child Health Journal·Babak KhoshnoodKwang-sun Lee
Feb 8, 2007·The American Journal of Clinical Nutrition·Robert L Goldenberg, Jennifer F Culhane
Jun 22, 2007·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Megan J WilsonLorna G Moore
Jun 27, 2008·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Colleen G JulianLorna G Moore
Dec 17, 2008·The Journal of Physiology·Lucrecia PostigoStacy Zamudio
Jan 6, 2010·PloS One·Stacy ZamudioNicholas P Illsley
Jul 3, 2010·Economics and Human Biology·George L WehbyJorge Lopez-Camelo
Dec 25, 2012·Obstetrics and Gynecology·Naho MorisakiEmily Oken

Citations

Dec 1, 2015·Wilderness & Environmental Medicine·Elizabeth JoyChristopher Madden
Sep 5, 2015·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Elizabeth JoyChristopher Madden
Apr 4, 2015·Journal of Perinatology : Official Journal of the California Perinatal Association·Thomas Waldhoer, K Klebermass-Schrehof
Jan 15, 2017·American Journal of Epidemiology·Lise Giorgis-AllemandRémy Slama
Jul 15, 2020·Journal of Developmental Origins of Health and Disease·Binyan ZhangShaonong Dang

Related Concepts

Altitude
Regression Analysis
Rietveld Refinement
Maternal Exposure
Birth
National Center for Health Statistics (U.S.)
Research
Health Care
Clinician
Analysis

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