A questionnaire on factors influencing children's assent and dissent to non-therapeutic research.

Journal of Medical Ethics
O D Wolthers

Abstract

Knowledge about assent or dissent of children to non-therapeutic research is poor. To assess sociodemographic characteristics in healthy children and adolescents who were invited to participate in non-therapeutic research, to evaluate their motives for assent or dissent and their understanding of the information given. A total of 1281 healthy children and adolescents six to sixteen years of age were invited to participate in a non-therapeutic study and a questionnaire. Assenting children were motivated by a desire to help sick children (n = 638, 98%) and to gain experience with participating in a research study (n = 503, 82%). Dissenting children made their decision because of worries about having a blood (n = 193, 46%) or a urine sample (n = 94, 26%) taken or because of worries about a doctor's examination (n = 136, 33%). Fewer children in the assent group (n = 166, 25%) than in the dissent group (136, 33%) worried about the doctor's examination (p = 0.01). In the assent and dissent group, 568 (86%) and 343 (85%) children, respectively, said they were able to understand some or all of the written information (p = 0.42), and 650 (97%) and 330 (98%), respectively, were able to understand some or all of the verbal information (p ...Continue Reading

References

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Citations

Aug 19, 2011·European Journal of Clinical Pharmacology·Tareq MukattashJames C McElnay
Apr 5, 2007·Archives of Disease in Childhood·J CherrillI Choonara
Oct 18, 2012·European Journal of Pediatrics·Wendy BosWim Pinxten
Aug 28, 2012·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Janet L BrodyJeanne Dalen
Oct 25, 2011·Patient Education and Counseling·Joke Aurelia Maria Hunfeld, Jan Passchier
Apr 15, 2010·Public Health Genomics·S van der PalS Detmar
May 9, 2014·Journal of Child Health Care : for Professionals Working with Children in the Hospital and Community·Jane CoadBernie Carter
Jan 10, 2012·Journal of Empirical Research on Human Research Ethics : JERHRE·Ulrica SwartlingAnders Nordgren
Mar 7, 2020·Frontiers in Pediatrics·Karolien Van De MaeleInge Gies

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