A rabbit model of fat graft recipient site preconditioning using external negative pressure

Archives of Plastic Surgery
Jung Woo LeeJin Hyung Park

Abstract

Fat is widely used in soft tissue augmentation. Nevertheless, it has an unpredictably high resorption rate. Clinically, external expansion with negative pressure is used to increase fat graft survival. In this study, fat graft recipient sites were preconditioned by external application of negative pressure in order to test for improvements in vascularity and fat graft survival. Negative pressure was applied randomly to either the left or right dorsal ear of 20 New Zealand male white rabbits at a pressure of -125 mm Hg. The negative pressure was removed one week after the skin perfusion was measured. The skin flap at each ear was elevated, and 1 g of fat was grafted above the dorsal perichondrium. After one week, the fat weight, microvessel density, mature vessel density of the skin and fat, and amount of glycerol released were measured. Three months after the grafting, the same measurements were performed, with the exception of glycerol release. The fat survival rate of the experimental group (75.4%±3.9%) was higher than that of the control group (53.1%±4.3%) (P<0.001). Skin perfusion was higher in the experimental group. The glycerol release in the experimental group was significantly higher than in the control. The microvesse...Continue Reading

References

Aug 15, 2000·The Laryngoscope·T NishimuraM Furukawa
Jan 5, 2002·Annals of Plastic Surgery·Stefan LangerKonrad Messmer
Apr 5, 2002·Plastic and Reconstructive Surgery·Cihat Nazmi BaranTurgut Ortak
Jul 19, 2005·Asian Journal of Surgery·Shao-Zong ChenLong-Shun Xu
Oct 4, 2006·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Masaki YazawaTatsuo Nakajima
Oct 6, 2007·Acta Oto-laryngologica·Etsuyo TamuraYasuhiko Tabata
Feb 3, 2009·Plastic and Reconstructive Surgery·Nicolas KairinosDonald A Hudson
Jan 11, 2011·Annals of Surgery·Paolo ErbaDennis P Orgill
Apr 5, 2011·Aesthetic Plastic Surgery·BoYoung ParkYang Woo Kim
Apr 16, 2011·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Dong Seok OhDae Hyun Lew
May 28, 2011·Plastic and Reconstructive Surgery·Daniel A Del Vecchio, Louis P Bucky
Feb 1, 2012·Diabetes/metabolism Research and Reviews·M V Schintler
Aug 30, 2012·Plastic and Reconstructive Surgery·Daniel Del Vecchio, Rod J Rohrich
May 30, 2013·Plastic and Reconstructive Surgery·Pierluigi GigliofioritoPaolo Persichetti
Feb 28, 2014·Plastic and Reconstructive Surgery·Roger K KhouriThomas M Biggs
Feb 28, 2014·Plastic and Reconstructive Surgery·Daniel A Del Vecchio, Sharon J Del Vecchio

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Citations

Nov 12, 2016·Indian Journal of Plastic Surgery : Official Publication of the Association of Plastic Surgeons of India·Raghuveer ReddyChaya Prasad
Apr 5, 2018·Plastic and Reconstructive Surgery. Global Open·Carlo M OrangesDirk J Schaefer
Mar 29, 2019·Plastic and Reconstructive Surgery·Carlo M OrangesDirk J Schaefer
Jun 17, 2016·Plastic and Reconstructive Surgery·Carlo M Oranges, Dirk J Schaefer
Jun 17, 2016·Plastic and Reconstructive Surgery·Jorge Lujan-HernandezDennis P Orgill
Aug 22, 2020·Tissue Engineering. Part B, Reviews·Xihang ChenYi Yuan

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Methods Mentioned

BETA
lipolysis
dissections
dissection

Software Mentioned

SPSS

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