A randomised comparison of medical and hysteroscopic management in women consulting a gynaecologist for treatment of heavy menstrual loss

British Journal of Obstetrics and Gynaecology
Kevin G CooperA Grant

Abstract

To compare medical with hysteroscopic management in women referred to a gynaecologist complaining of heavy menstrual loss. Single-centre randomised trial. A teaching hospital in the United Kingdom. One hundred and ninety-seven women seeking specialist treatment of heavy menstrual loss for the first time and willing to accept either treatment. 1. Medical treatments not previously used by the women prescribed by experienced gynaecologists in standard doses and timings for a minimum of three cycles (n = 94), and 2. transcervical resection of the endometrium performed under general anaesthesia five weeks after goserelin preparation (n = 93). Treatment satisfaction and acceptability, relief of symptoms, change in haemoglobin, and improvement in health related quality of life, all after four months. Women allocated transcervical resection were more likely to be totally or generally satisfied (76% versus 27%, P < 0.001), to find the treatment acceptable (93% versus 36%, P < 0.001), and willing to have the treatment again (93% versus 31%, P < 0.001). Although pain and bleeding were significantly reduced by medical treatment this was modest in comparison with transcervical resection (P < 0.001). Haemoglobin levels were significantly inc...Continue Reading

References

Oct 1, 1992·Journal of Clinical Epidemiology·J A Knottnerus, P Leffers
Feb 1, 1991·The Australian & New Zealand Journal of Obstetrics & Gynaecology·I S Fraser, G McCarron
Aug 1, 1990·British Journal of Obstetrics and Gynaecology·J K Andersson, G Rybo
Nov 1, 1990·The Australian & New Zealand Journal of Obstetrics & Gynaecology·I S Fraser
Jul 1, 1989·British Journal of Obstetrics and Gynaecology·C J DockerayJ Bonnar
Aug 1, 1967·Journal of Chronic Diseases·D Schwartz, J Lellouch
Jun 1, 1983·Acta Psychiatrica Scandinavica·A S Zigmond, R P Snaith
Dec 1, 1980·British Journal of Obstetrics and Gynaecology·T H ChimbiraA C Turnbull
Feb 1, 1995·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·D A RutaI T Russell
Oct 1, 1994·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·C JenkinsonA Coulter
Nov 1, 1994·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·R PittrofA Murray
Feb 1, 1994·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·C JenkinsonA Coulter
Mar 1, 1993·British Journal of Obstetrics and Gynaecology·M J SculpherG M Stirrat
May 29, 1993·BMJ : British Medical Journal·J E Ware
May 29, 1993·BMJ : British Medical Journal·A M GarrattI T Russell

❮ Previous
Next ❯

Citations

Nov 4, 2010·Archives of Gynecology and Obstetrics·Adel Saad HelalLotfy Sherif
Mar 24, 2004·Maturitas·Marlies Y BongersHans A M Brölmann
Jun 8, 2002·Obstetrics and Gynecology·Christine BainDavid E Parkin
Jun 8, 2002·Obstetrics and Gynecology·M Y BongersH A M Brölmann
Apr 30, 1999·Journal of Nurse-midwifery·J L EngstromL Fritz
Jan 15, 2002·European Journal of Obstetrics, Gynecology, and Reproductive Biology·U H Winkler
Sep 11, 2002·European Journal of Obstetrics, Gynecology, and Reproductive Biology·T Justin ClarkJanesh K Gupta
Aug 19, 2000·Clinical Obstetrics and Gynecology·D N Kammerer-Doak, R G Rogers
Aug 19, 2000·Clinical Obstetrics and Gynecology·A P Korn
May 22, 2007·Clinical Obstetrics and Gynecology·Malcolm G Munro
Sep 10, 1999·BMJ : British Medical Journal·C Kelleher, P Braude
Dec 4, 2003·BMJ : British Medical Journal·Anne Lethaby, Cindy Farquhar
Aug 24, 2013·ISRN Obstetrics and Gynecology·Sule GokyildizMeltem Mecdi
Jul 15, 2009·Journal de gynécologie, obstétrique et biologie de la reproduction·H RomanL Marpeau
Mar 1, 2012·Journal of Women's Health·Jeffrey T JensenMei Sheng Duh
Apr 5, 2013·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·R Kirkwood-WilsonS Das
Oct 30, 2004·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·M P Milligan, G A Etokowo
Dec 18, 2015·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Josien P M PenninxMarlies Y Bongers
Aug 7, 2010·European Journal of Obstetrics, Gynecology, and Reproductive Biology·H MarretUNKNOWN CNGOF Collège National des Gynécologues et Obstétriciens Français
Oct 13, 2009·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Marwan HabibaAla Szczepura
May 15, 2007·Best Practice & Research. Clinical Obstetrics & Gynaecology·Olav Istre, Erik Qvigstad
Jan 24, 2006·Best Practice & Research. Clinical Obstetrics & Gynaecology·Chris Sutton
Jul 19, 2005·Best Practice & Research. Clinical Obstetrics & Gynaecology·Kevin G Cooper
Sep 9, 2005·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·B SharmaC Ray
Sep 9, 2005·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·T El-ToukhyJ Erian
Aug 24, 2002·American Journal of Obstetrics and Gynecology·Georgina L JonesCrispin Jenkinson
May 30, 2007·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Zhimei LiuRobert W Dubois
Dec 21, 2002·Best Practice & Research. Clinical Anaesthesiology·Mary C Mushambi, Karin Williamson
Feb 24, 2001·BJOG : an International Journal of Obstetrics and Gynaecology·C Kremer, S Duffy
Nov 4, 1998·British Journal of Obstetrics and Gynaecology·R A McMaster-Fay
Jul 1, 1998·British Journal of Obstetrics and Gynaecology·K Duckitt, R W Shaw
Sep 24, 2004·BJOG : an International Journal of Obstetrics and Gynaecology·Marlies Y BongersHans A M Brölmann
Dec 13, 2003·Journal of Women's Health·Karen BarnardLisa M Sullivan
May 4, 2000·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·M Y BongersH A Brölmann
Jun 19, 2002·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Richard HenshawChristopher Barry
Oct 27, 2007·Haemophilia : the Official Journal of the World Federation of Hemophilia·M ShankarR A Kadir
Jan 29, 2016·The Cochrane Database of Systematic Reviews·Jane MarjoribanksCindy Farquhar
Sep 5, 2001·Acta Obstetricia Et Gynecologica Scandinavica·F WieserF Nagele

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Landau-Kleffner Syndrome

Landau Kleffner syndrome (LKS), also called infantile acquired aphasia, acquired epileptic aphasia, or aphasia with convulsive disorder, is a rare childhood neurological syndrome characterized by the sudden or gradual development of aphasia (the inability to understand or express language) and an abnormal electroencephalogram. Discover the latest research on LKS here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.