A randomised controlled comparison of early post-pyloric versus early gastric feeding to meet nutritional targets in ventilated intensive care patients.

Critical Care : the Official Journal of the Critical Care Forum
Hayden WhiteMark Jones

Abstract

To compare outcomes from early post-pyloric to gastric feeding in ventilated, critically ill patients in a medical intensive care unit (ICU). Prospective randomized study. Ventilated patients were randomly assigned to receive enteral feed via a nasogastric or a post-pyloric tube. Post-pyloric tubes were inserted by the bedside nurse and placement was confirmed radiographically. A total of 104 patients were enrolled, 54 in the gastric group and 50 in the post-pyloric group. Bedside post-pyloric tube insertion was successful in 80% of patients. Patients who failed post-pyloric insertion were fed via the nasogastric route, but were analysed on an intent-to treat basis. A per protocol analysis was also performed. Baseline characteristics were similar for all except Acute Physiology and Chronic Health Evaluation II (APACHE II) score, which was higher in the post-pyloric group. There was no difference in length of stay or ventilator days. The gastric group was quicker to initiate feed 4.3 hours (2.9 - 6.5 hours) as compared to post-pyloric group 6.6 hours (4.5 - 13.0 hours) (P = 0.0002). The time to reach target feeds from admission was also faster in gastric group: 8.7 hours (7.6 - 13.0 hours) compared to 12.3 hours (8.9 - 17.5 hour...Continue Reading

References

Jul 1, 1979·Radiology·F C ShippsJ M Jones
Dec 1, 1992·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·P J UgoG L Wilson
Mar 1, 1991·Archives of Internal Medicine·G D WendellR A Promisloff
Jul 1, 1989·The Journal of Trauma·F A MooreV M Peterson
Jan 1, 1986·JPEN. Journal of Parenteral and Enteral Nutrition·P M Thurlow
Oct 1, 1987·Digestive Diseases and Sciences·A M KoolsO W Cass
Apr 1, 1995·Southern Medical Journal·A E HillardD McAlpin
Oct 1, 1996·Critical Care Medicine·C R Hernández-SocorroJ L Manzano
Dec 1, 1996·Intensive Care Medicine·D K HeylandD J Cook
Mar 1, 1997·Intensive Care Medicine·M M TarlingD R Goldhill
Jul 11, 1998·Critical Care Medicine·R SalasidisR Johnston
Jul 22, 1998·The American Journal of Gastroenterology·C H KaoT C Yen
Mar 25, 1999·Burns : Journal of the International Society for Burn Injuries·T D ChouH J Wang
Jan 22, 2002·Critical Care Medicine·P E Marik, G P Zaloga
Apr 10, 2002·Critical Care Medicine·Juan C MontejoUNKNOWN Nutritional and Metabolic Working Group of the Spanish Society of Intensive Care Medicine and Coronary Units
May 7, 2002·Critical Care Medicine·Andrew R DaviesRichard B Sewell
Jul 20, 2002·Critical Care Medicine·Daniel A Neumann, Mark H DeLegge
Jun 10, 2003·Critical Care : the Official Journal of the Critical Care Forum·Paul E Marik, Gary P Zaloga
Sep 16, 2003·JPEN. Journal of Parenteral and Enteral Nutrition·Daren K HeylandUNKNOWN Canadian Critical Care Clinical Practice Guidelines Committee
Apr 15, 2004·JPEN. Journal of Parenteral and Enteral Nutrition·Sabry A Gabriel, Richard J Ackermann
Feb 9, 2005·Critical Care Medicine·Gary P Zaloga
May 19, 2005·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Stéphane VilletMette M Berger
May 16, 2006·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·K G KreymannUNKNOWN ESPEN (European Society for Parenteral and Enteral Nutrition)
Nov 23, 2006·Intensive Care Medicine·Sonja FruhwaldHelfried Metzler
Feb 10, 2007·Critical Care : the Official Journal of the Critical Care Forum·Nam Q NguyenRichard H Holloway
May 4, 2007·International Urology and Nephrology·Denis Fouque, Fitsum Guebre-Egziabher
Jul 24, 2007·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Rebecca GrayJacquelyn Neylon
Aug 1, 2007·World Journal of Gastroenterology : WJG·Adam DeaneNam Q Nguyen
Dec 31, 2008·Critical Care Medicine·Marcel Gatt, John MacFie

❮ Previous
Next ❯

Citations

Jun 7, 2013·Medizinische Klinik, Intensivmedizin und Notfallmedizin·C Madl, U Holzinger
Mar 21, 2012·Critical Care : the Official Journal of the Critical Care Forum·Andrea CoppadoroLorenzo Berra
Sep 19, 2012·Critical Care : the Official Journal of the Critical Care Forum·Anna E Di BartolomeoAdam M Deane
Jun 27, 2013·Critical Care : the Official Journal of the Critical Care Forum·Adam M DeaneK Heyland Daren
Jul 4, 2013·Critical Care : the Official Journal of the Critical Care Forum·Waleed AlhazzaniAlison E Fox-Robichaud
Mar 20, 2010·Critical Care : the Official Journal of the Critical Care Forum·Mette M Berger, Ludivine Soguel
Dec 3, 2010·Critical Care : the Official Journal of the Critical Care Forum·Vincent Huberlant, Jean-Charles Preiser
Feb 26, 2014·Annales Françaises D'anesthèsie Et De Rèanimation·J-Y LefrantUNKNOWN Société francophone nutrition clinique et métabolique
Jun 1, 2013·European Journal of Trauma and Emergency Surgery : Official Publication of the European Trauma Society·M TunaH Al Thani
Jan 30, 2016·Journal of Veterinary Emergency and Critical Care·KimMi WhiteheadLaura Eirmann
Nov 5, 2013·The Medical Clinics of North America·T Miko EnomotoRobert G Martindale
Aug 3, 2012·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Jing JiyongJin Jingfen
May 7, 2014·Chest·Svetang V DesaiTodd W Rice
Mar 14, 2012·Medicina intensiva·A L Blesa MalpicaUNKNOWN Spanish Society of Intensive Care Medicine and Coronary Units-Spanish Society of Parenteral and Enteral Nutrition (SEMICYUC-
Nov 22, 2011·Gastroenterology Clinics of North America·Marianne J ChapmanAdam M Deane
Dec 1, 2010·Burns : Journal of the International Society for Burn Injuries·S J Hemington-GorseP Dziewulski
Dec 15, 2015·Australian Critical Care : Official Journal of the Confederation of Australian Critical Care Nurses·Duygu Sönmez Düzkaya, Suzan Yildiz
Jan 20, 2016·Expert Opinion on Drug Delivery·Wouter F W KappelleFrank P Vleggaar
Nov 7, 2016·Critical Care : the Official Journal of the Critical Care Forum·Hasan M Al-DorziYaseen M Arabi
Nov 7, 2016·JPEN. Journal of Parenteral and Enteral Nutrition·Joseph I BoullataUNKNOWN ASPEN Safe Practices for Enteral Nutrition Therapy Task Force, American Society for Parenteral and Enteral Nutrition
Jun 21, 2014·JPEN. Journal of Parenteral and Enteral Nutrition·Delara SaranDaren K Heyland
Feb 28, 2016·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Kirsten Schlein
Aug 12, 2015·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Zhuo LiNiranjan Kissoon
Apr 26, 2013·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Zhongheng ZhangHongying Ni
Jun 30, 2016·Journal of Burn Care & Research : Official Publication of the American Burn Association·Alan W YoungTina Palmieri
Jul 6, 2014·The American Journal of Clinical Nutrition·Sandra L PeakeUNKNOWN TARGET investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group
Aug 5, 2015·The Cochrane Database of Systematic Reviews·Sana AlkhawajaFemida Gwadry-Sridhar
Feb 28, 2015·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Gilberto FriedmanMaicon Becker
Oct 1, 2011·Therapeutic Advances in Drug Safety·Nam Q Nguyen, Swee Lin Chen Yi Mei
Jan 29, 2013·Critical Care Medicine·Patrícia ZamberlanArtur Figueiredo Delgado
Jul 20, 2012·Critical Care Medicine·Andrew R DaviesUNKNOWN ANZICS Clinical Trials Group
Jan 22, 2013·Current Opinion in Clinical Nutrition and Metabolic Care·Marianne J ChapmanAdam M Deane
Aug 5, 2016·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Alejandro A FlohSteven M Schwartz
Sep 3, 2014·American Journal of Critical Care : an Official Publication, American Association of Critical-Care Nurses·Friederike ComptonMarkus van der Giet
Dec 5, 2019·Trauma Surgery & Acute Care Open·Lewis E JacobsonDonald F Kirby
May 2, 2018·Clinical Nutrition Research·Maryam ShabanpurMehnoosh Samadi
Oct 26, 2013·The Journal of Trauma and Acute Care Surgery·Evan S GlazerPeter M Rhee
Nov 30, 2013·Journal of Hospital Medicine : an Official Publication of the Society of Hospital Medicine·Nathan BoyerCristin A Mount
Sep 13, 2017·Molecular and Clinical Oncology·Hong-Wei ZhangGuo-Cai Li

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