A randomised controlled trial of injection therapy versus neurectomy for post-herniorrhaphy inguinal neuralgia: rationale and study design.

Hernia : the Journal of Hernias and Abdominal Wall Surgery
Maarten J A LoosRudi M Roumen

Abstract

Chronic inguinal neuralgia is considered to be an important complication after hernia repair. As a high-level evidence-based treatment regime is currently lacking, these patients usually receive a random combination of pain medication, local nerve blocks or an occasional surgical neurectomy. A controlled trial ('GroinPain Trial') was constructed to identify the optimal treatment modality in this population. The aim and rationale of the trial are presented in this paper. Adult patients with chronic post-herniorrhaphy inguinal pain (>3 months) caused by inguinal nerve entrapment having a temporary pain reduction after a lidocain nerve block are eligible for randomisation. They received either repetitive nerve blocks with lidocain, corticosteroids and hyaluronic acid, or a 'tailored' surgical neurectomy. Patient enrollment started in February 2006 and is expected to end in June 2010. The initial results will be available at the end of 2010. This trial is the first randomised controlled effort comparing two invasive treatment modalities for peripheral inguinal nerve entrapment. As awareness and knowledge on chronic neuropathic pain after inguinal herniorrhaphy in the near future is expected to increase, the findings of this trial w...Continue Reading

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Oct 16, 2009·Surgery·Maarten J LoosRudi M Roumen

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Citations

Nov 16, 2012·Journal of Pain Research·Igor Kissin, Simon Gelman
Jul 19, 2011·World Journal of Gastrointestinal Surgery·Abdul Hakeem, Venkatesh Shanmugam
May 23, 2014·Langenbeck's Archives of Surgery·Mads U Werner
Sep 28, 2012·Hernia : the Journal of Hernias and Abdominal Wall Surgery·I ThomassenS W Nienhuijs
Sep 6, 2014·World Journal of Surgery·T van AssenR M Roumen
May 28, 2011·Acta Obstetricia Et Gynecologica Scandinavica·Lennart Hahn
Mar 19, 2019·European Journal of Anaesthesiology·Pierre BlancUNKNOWN EDONIS-gene Investigating group

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