A randomised, controlled trial of the pulmonary artery catheter in critically ill patients

Intensive Care Medicine
Andrew RhodesE D Bennett

Abstract

To compare the survival and clinical outcomes of critically ill patients treated with the use of a pulmonary artery catheter (PAC) to those treated without the use of a PAC. Prospective, randomised, controlled, clinical trial from October 1997 to February 1999. Adult intensive care unit at a large teaching hospital. Two hundred one critically ill patients were randomised either to a PAC group ( n=95) or the control group ( n=106). One patient in the control group was withdrawn from the study and five patients in the PAC group did not receive a PAC. All participants were available for follow-up. Participants were assigned to be managed either with the use of a PAC (PAC group) or without the use of a PAC (control group). Survival to 28 days, intensive care and hospital length of stay and organ dysfunction were compared on an intention-to-treat basis and also on a subgroup basis for those participants who successfully received a PAC. RESULTS There was no significant difference in mortality between the PAC group [46/95 (47.9%)] and the control group [50/106 (47.6)] (95% confidence intervals for the difference -13 to 14%, p>0.99). The mortality for participants who had management decisions based on information derived from a PAC was...Continue Reading

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