A randomized clinical trial of a weight loss maintenance intervention in a primary care population

Obesity
Adam G TsaiJames O Hill

Abstract

In-person weight loss maintenance visits have been shown to reduce weight regain after initial weight loss. This study examined, in a primary care population, whether in-person visits plus portion-controlled meals were more effective in reducing 12-month weight regain than mailed materials plus portion controlled meals. Study participants (n = 106) received 6 months of intensive behavioral treatment. Participants who completed this phase (n = 84) were then randomized to continue monthly in-person visits for weight loss maintenance as well as telephone calls between visits ("intensified maintenance") or to receive materials by mail ("standard maintenance"). All participants had access to subsidized portion-controlled foods during the 6-month run-in and the 12 months of maintenance. The primary outcome was weight change during the 12 months after randomization. During months 0-12 after randomization, individuals assigned to standard maintenance regained 5.3% ± 0.8% of body weight, while those assigned to intensified maintenance regained 1.6% ± 1.2% of body weight. The difference between groups (3.7% ± 1.4%) was statistically significant (P = 0.01). In a primary care population, continued in-person visits during the weight loss ma...Continue Reading

References

Feb 16, 1999·The American Journal of Clinical Nutrition·H H DitschuneitG Adler
Jun 5, 1999·The American Journal of Clinical Nutrition·J O HillL J Aronne
Nov 28, 2002·Diabetes Care·UNKNOWN Diabetes Prevention Program (DPP) Research Group
Apr 22, 2003·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·S B HeymsfieldH I Frier
Sep 22, 2006·Obesity·Adam Gilden Tsai, Thomas A Wadden
Oct 13, 2006·The New England Journal of Medicine·Rena R WingJoseph L Fava
Mar 13, 2008·JAMA : the Journal of the American Medical Association·Laura P SvetkeyUNKNOWN Weight Loss Maintenance Collaborative Research Group
Aug 19, 2011·BMC Health Services Research·Adam G TsaiLorraine G Ogden
Nov 17, 2011·The New England Journal of Medicine·Lawrence J AppelFrederick L Brancati
Mar 14, 2012·Archives of Internal Medicine·Gary G BennettUNKNOWN Be Fit, Be Well Study Investigators
Jun 27, 2012·Annals of Internal Medicine·Virginia A Moyer, UNKNOWN U.S. Preventive Services Task Force
Jul 3, 2013·International Journal of Obesity : Journal of the International Association for the Study of Obesity·T A WaddenUNKNOWN NN8022-1923 Investigators
Sep 6, 2013·The New England Journal of Medicine·Majid Ezzati, Elio Riboli
Nov 5, 2014·JAMA : the Journal of the American Medical Association·Thomas A WaddenAdam G Tsai
Feb 16, 2015·The Lancet. Diabetes & Endocrinology·Christopher N OchnerThomas A Wadden

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Citations

Feb 11, 2016·Current Pain and Headache Reports·Cynthia CervoniElizabeth K Seng
Dec 8, 2016·American Journal of Men's Health·Melissa M CraneNancy E Sherwood
Jul 1, 2017·Journal of Sleep Research·Elizabeth A CayananRonald R Grunstein
Jan 25, 2018·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·L B van der HeijdenA J Janse
Mar 20, 2019·Current Obesity Reports·Jena Shaw TronieriAdam Gilden Tsai
Nov 12, 2019·Annals of Internal Medicine·Molly B ConroyGary S Fischer
Feb 18, 2018·BMJ Open·Elizabeth A SturgissKirsty A Douglas
Aug 6, 2015·Journal of Pediatric Endocrinology & Metabolism : JPEM·Emil PolákĽudevít Kádaši
Jul 15, 2015·Hormone Molecular Biology and Clinical Investigation·Ciara H O'FlanaganStephen D Hursting
Feb 18, 2021·The Journal of Clinical Endocrinology and Metabolism·Karim KheniserSangeeta R Kashyap

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