Abstract
ERCP is a complex procedure often performed in patients at high risk for sedation-related adverse events (SRAEs). However, there is no current standard of care with regard to mode of sedation and airway management during ERCP. The aim of this study was to assess the safety of general endotracheal anesthesia (GEA) versus propofol-based monitored anesthesia care (MAC) without endotracheal intubation in patients undergoing ERCP at high risk for SRAEs. Consecutive patients undergoing ERCP at high risk for SRAEs at a single center were invited to participate in this randomized controlled trial comparing GEA and MAC. Inclusion criteria were STOP-BANG score ≥3, abdominal ascites, body mass index ≥35, chronic lung disease, American Society of Anesthesiologists class >3, Mallampati class 4 airway, and moderate to heavy alcohol use. Exclusion criteria were preceding EUS, emergent ERCP, tracheostomy, unstable airway, gastric outlet obstruction or delayed gastric emptying, and altered foregut anatomy. The primary endpoint was composite incidence of SRAEs: hypoxemia, use of airway maneuvers, hypotension requiring vasopressors, sedation-related procedure interruption, cardiac arrhythmia, and respiratory failure. Secondary outcomes included p...Continue Reading
Citations
Mar 16, 2019·Minerva anestesiologica·Luca AielloStefano Maitan
Apr 18, 2019·Current Opinion in Anaesthesiology·Zachary L SmithVladimir M Kushnir
Nov 23, 2019·Anesthesiology and Pain Medicine·Ahmad HormatiHamed Shafiee
Sep 19, 2019·Scandinavian Journal of Gastroenterology·Liv Bjerre Juul NielsenLars Tue Sørensen
Mar 7, 2020·Frontline Gastroenterology·Zachary L SmithVladimir M Kushnir
May 30, 2020·BMC Anesthesiology·Chengcheng C ZhangAnja Schaible
Jun 7, 2020·Digestive Diseases and Sciences·Monique T BarakatSubhas Banerjee
Jul 10, 2020·Digestive Diseases and Sciences·Tilak Shah, Stefan Ianchulev
Oct 21, 2020·Anesthesia and Analgesia·Katherine B HaganCarin A Hagberg
Oct 31, 2020·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Takuji GotodaHaruhiro Inoue
Oct 14, 2020·British Journal of Anaesthesia·Friederike C AlthoffMatthias Eikermann
May 7, 2021·Canadian Journal of Gastroenterology & Hepatology·Ahmed AkhterPatrick Pfau
May 6, 2021·United European Gastroenterology Journal·Bing ChenChien-Chang Lee
May 10, 2021·Surgical Endoscopy·Thomas R McCartyChristopher C Thompson
Jun 29, 2021·Anaesthesia·V ThiruvenkatarajanUNKNOWN collaborators
Aug 25, 2021·Geriatrics & Gerontology International·Salih TokmakSerkan Torun
Feb 20, 2021·Journal of Minimal Access Surgery·Pavlos AntypasGianfranco Donatelli
May 14, 2021·Minerva anestesiologica·Harun UysalKazim Karaaslan
Dec 3, 2021·Geriatrics & Gerontology International·Nong HeFu-Shan Xue
Jan 15, 2022·Journal of Clinical Anesthesia·Kuo-Chuan HungCheuk-Kwan Sun