A randomized controlled trial of a 10 week group psychotherapeutic treatment added to standard medical treatment in patients with functional dyspepsia

Journal of Psychosomatic Research
M OriveJ M Quintana

Abstract

Epidemiological evidence suggests an association between psychological factors and functional dyspepsia (FD). Yet few randomized controlled trials (RCTs) of psychological interventions have been conducted for FD. We conducted an RCT to evaluate the efficacy of psychotherapy among chronic FD. One hundred fifty-eight consecutive patients with FD were randomized to medical therapy plus psychotherapy consisted in 8 group and 2 individual sessions focused on teaching techniques for coping with FD (intensive treatment (IT); n=76) or medical therapy alone (conventional treatment (CT); n=82). Patients completed validated self-reported questionnaires before and after the 10-week treatment and 6 months later. Linear mixed-effects models were used, in intention-to-treat analysis. At the end of treatment period, statistically significant improvements were observed for IT compared with CT for dyspepsia-related quality of life (DRQoL). DRQoL mean changes of 6.09 and 3.54 were obtained in IT and CT patients, respectively (p=<0.0001); and SS mean changes of 11.55 and 4.57 were obtained in IT and CT patients, respectively (p=0.0013). Those improvements, measured by minimum clinically important difference (MCID), were clinically significant (DRQ...Continue Reading

Associated Clinical Trials

Mar 1, 2013·Miren Orive CalzadaMiren Orive Calzada
Mar 21, 2019·Sarah Kinsinger

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Citations

Apr 29, 2015·Journal of Gastroenterology·Nicholas J TalleyMarjorie M Walker
Nov 5, 2015·The New England Journal of Medicine·Nicholas J Talley, Alexander C Ford
Apr 7, 2016·The Korean Journal of Internal Medicine·Nicholas J Talley
Jun 30, 2016·Expert Review of Gastroenterology & Hepatology·Bonney Reed-KnightMiranda A L van Tilburg
Jun 21, 2017·The American Journal of Gastroenterology·Paul M MoayyediNimish Vakil
Nov 17, 2017·Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva·Miren OriveJosé María Quintana
Sep 22, 2018·Expert Review of Clinical Immunology·Mounika AddulaDevendra K Agrawal
Dec 5, 2018·Journal of Neurogastroenterology and Motility·Beom Jin Kim, Braden Kuo
Nov 4, 2017·Nature Reviews. Disease Primers·Paul EnckNicholas J Talley
Jun 5, 2019·European Journal of Gastroenterology & Hepatology·Song LinAiguo Ma
Jan 10, 2020·Journal of Neurogastroenterology and Motility·Jung Hwan OhUNKNOWN Functional Dyspepsia Research Group and Clinical Practice Guidelines Group Under the Korean Society of Neurogastroenterology
Nov 22, 2019·Journal of Neurogastroenterology and Motility·Yen-Po WangChing-Liang Lu
Jul 22, 2020·Drugs·Gregory S Sayuk, C Prakash Gyawali
Apr 19, 2017·MMW Fortschritte der Medizin·Constanze H WaggershauserMartin Storr
Jun 5, 2020·Current Gastroenterology Reports·Olafur S Palsson, Sarah Ballou
Mar 30, 2019·Alimentary Pharmacology & Therapeutics·Imke MasuyJan Tack
Oct 8, 2020·Research in Psychotherapy : Psychopathology, Process, and Outcome·Sepideh BatebiMohammad Hasan Davazdah Emami
Dec 30, 2020·Journal of Gastroenterology and Hepatology·Kevin Kim-Jun TehYu-Tien Wang
Apr 20, 2018·Deutsches Ärzteblatt International·Ahmed MadischMichael Schemann
Oct 23, 2020·Journal of Research in Medical Sciences : the Official Journal of Isfahan University of Medical Sciences·Tahmine TavakoliBita Bijari
Jun 10, 2021·Journal of Gastroenterology and Hepatology·David M RodriguesMichael J Beyak

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