A randomized controlled trial on the psychophysiological effects of physical exercise and Tai-chi in patients with chronic schizophrenia

Schizophrenia Research
Rainbow Tin Hung HoEric Yu Hai Chen

Abstract

The chronic and prevalent natures of schizophrenia result in long-term institutionalization for the patients. Conventional treatment of anti-psychotic medication on management of psychotic symptoms often brings on severe side effects and reduces patients' well-being. Tai-chi is a mind-body exercise that underscores motor coordination and relaxation. This 3-arm randomized controlled trial investigated the psychophysiological benefits of Tai-chi on 153 chronic schizophrenia patients, who were recruited from a mental health rehab complex and randomized into Tai-chi, exercise, or waitlist control groups. Both intervention groups received 12weeks of specific intervention plus standard medication received by the controls. All participants completed psychiatric interviews, self-report questionnaires, performance tasks, and salivary cortisol measures at baseline, 3-month, and 6-month follow-up on psychotic symptoms, motor coordination, memory, daily living function, and stress. Multigroup latent growth modeling was used to evaluate the intervention effects on the outcomes. Compared to controls, the Tai-chi group showed significant decreases in motor deficits and increases in backward digit span and mean cortisol, while the exercise gro...Continue Reading

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Citations

Mar 22, 2016·Journal of Affective Disorders·Matias Carvalho Aguiar MeloVeralice Meireles Sales de Bruin
Aug 17, 2006·Complementary Therapies in Medicine·Kuei-Min ChenMin-Feng Huang
Nov 14, 2016·Psychiatry Research·Mehala SubramaniapillaiGuy Faulkner
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Mar 9, 2018·Clinical Practice and Epidemiology in Mental Health : CP & EMH·Federica SancassianiAntonio Preti
Nov 17, 2020·Frontiers in Psychiatry·Fuzhong YangHua Xiao
Mar 30, 2021·Evidence-based Complementary and Alternative Medicine : ECAM·Jiafu HuangJinghao Wang
Jul 13, 2021·Clinical Practice and Epidemiology in Mental Health : CP & EMH·Antonio RampinoSilvia Torretta
Aug 17, 2021·Evidence-based Complementary and Alternative Medicine : ECAM·Renjun GuZhiguang Sun
Mar 19, 2019·Psychiatry Research·Jelle Sjoerd VogelStynke Castelein

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