A randomized prospective study comparing medical and medical-surgical treatment of nasal polyposis by CT

Acta Oto-laryngologica
Ebba Hedén BlomqvistPär Stjärne

Abstract

CT of the sinuses showed long-lasting improvement in the total and CT scores of the osteomeatal complex (OMC) after combined surgical and corticosteroid treatment as compared with medical treatment alone. However, the correlations between the improved CT scores and the patients' symptoms, olfactory thresholds or polyp scores were generally not significant. To evaluate CT scans as a method for comparing the effect of medical treatment versus combined surgical and medical treatment of nasal polyposis. Thirty-two patients with nasal polyposis were randomized to unilateral endoscopic sinus surgery after pretreatment with oral prednisolone for 10 days and nasal budesonide bilaterally for 1 month. Postoperatively, they were given nasal steroids (budesonide) bilaterally for 1 year. They were assessed with nasal endoscopy, symptom scores, and olfactory thresholds and followed for 12 months. CT of the sinuses was performed before and 1 year after operation. The CT scans were evaluated using the Lund staging system. From before surgery to 1 year after surgery, we found a significant improvement on the operated side in the CT total scores, and scores of the OMC and the maxillary sinus, but no significant differences on the unoperated side...Continue Reading

References

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Citations

Feb 25, 2011·International Archives of Allergy and Immunology·Claus Bachert
May 24, 2013·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Mohammad Hossein BaradaranfarTohid Emami Meybodi
Feb 22, 2014·Current Allergy and Asthma Reports·Christos GeorgalasWytske Fokkens
Jul 11, 2014·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·S Hancer TecimerO Basut
Jul 10, 2016·The Journal of Allergy and Clinical Immunology. in Practice·Robert M Naclerio, Fuad M Baroody
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Apr 27, 2016·The Cochrane Database of Systematic Reviews·Karen HeadAnne G M Schilder
Apr 27, 2016·The Cochrane Database of Systematic Reviews·Karen HeadMartin J Burton
Aug 22, 2009·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Jelka LindicAndrej Bren
Apr 26, 2016·The Cochrane Database of Systematic Reviews·Pablo Martinez-Devesa, Shalini Patiar

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