A randomized study of the safety of outpatient care for patients with bleeding peptic ulcer treated by endoscopic injection

Gastrointestinal Endoscopy
E BrulletJoan Cabrol

Abstract

Outpatient management is safe for patients with non-variceal upper-GI bleeding who are at low risk of recurrent bleeding and death. However, outpatient care cannot be offered to many patients because of the presence of risk factors (severe comorbid disorders, major endoscopic stigmata of bleeding, significant hemorrhage). The present study assessed the safety of outpatient management for selected high-risk patients with bleeding peptic ulcer. Patients hospitalized with upper-GI bleeding because of peptic ulcer with a non-bleeding vessel were eligible for inclusion in the study. Inclusion criteria were the following: ulcer size less than 15 mm, absence of hypovolemia, no associated severe disease, and appropriate family support. After endoscopic therapy (injection of epinephrine and polidocanol), patients were randomized to outpatient or hospital care. Patients remained in the emergency ward for a minimum of 6 hours before discharge, during which time omeprazole was administered intravenously. Outpatients were contacted by telephone daily during the first 3 days; a 24-hour telephone hotline was provided for any queries. For both groups, outpatient visits were scheduled at 7 to 10 and 30 days after discharge. A total of 82 patien...Continue Reading

References

Oct 1, 1978·Anesthesiology·W D OwensE L Spitznagel
Sep 15, 1994·The New England Journal of Medicine·L Laine, W L Peterson
Feb 1, 1996·Gastrointestinal Endoscopy·E BrulletL Donoso
Jan 7, 1998·JAMA : the Journal of the American Medical Association·J A HayA G Ellrodt
May 11, 1999·The American Journal of Gastroenterology·F Cebollero-SantamariaR Perrillo
Jun 26, 2001·Alimentary Pharmacology & Therapeutics·J P GisbertJ M Pajares
Jan 5, 2002·Gastrointestinal Endoscopy·Livio CipollettaRoberto Piscopo
Jul 30, 2002·Gastrointestinal Endoscopy·Benoit CoffinUNKNOWN Groupe des endoscopistes de garde á l'AP-HP

❮ Previous
Next ❯

Citations

Jan 20, 2006·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·M-A Ortner, G Dorta
Oct 29, 2013·Best Practice & Research. Clinical Gastroenterology·Sunny H Wong, Joseph J Y Sung
Jun 22, 2012·World Journal of Gastroenterology : WJG·Adrian J Stanley
Oct 18, 2011·Gastroenterología y hepatología·Francisco José Martínez CerezoCristina Manso
Jul 24, 2007·Gastrointestinal Endoscopy·Walter G ParkGeorge Triadafilopoulos
Jun 27, 2007·Gastrointestinal Endoscopy·Joseph CroffieBret T Petersen
Sep 9, 2011·Alimentary Pharmacology & Therapeutics·P García-IglesiasX Calvet
Mar 28, 2006·Gastrointestinal Endoscopy·G S Dulai
Feb 24, 2016·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Mitsuhiro FujishiroKazuma Fujimoto
Nov 12, 2015·World Journal of Gastrointestinal Pharmacology and Therapeutics·Erwin Biecker
Oct 21, 2006·Current Opinion in Gastroenterology·Noel B Martins, Wahid Wassef
Jul 15, 2009·Nature Reviews. Gastroenterology & Hepatology·Kelvin K F TsoiJoseph J Y Sung
Aug 8, 2008·The American Journal of Gastroenterology·B Joseph ElmunzerLoren Laine
Aug 31, 2021·Scandinavian Journal of Gastroenterology·Yo KubotaSatoshi Tanabe

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.