A randomized trial of automated versus conventional protocol-driven weaning from mechanical ventilation following coronary artery bypass surgery

European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
Holger HendrixJohannes Merk

Abstract

The Siemens servo 300 A ventilator has an automode function that allows automated weaning of patients from mechanical ventilation. Spontaneous breathing triggers the ventilator. After two spontaneously triggered breaths, the ventilator automatically changes from mandatory mechanical ventilation to spontaneous ventilation. If spontaneous breathing or triggering does not occur, the Siemens servo 300 A ventilator changes from spontaneous ventilation back to mandatory mechanical ventilation. We compared the effects of automated versus conventional protocol-driven weaning on the time until extubation in patients undergoing coronary artery bypass graft (CABG) surgery. In addition, we studied the effects of the mode of weaning on hemodynamic and physiologic parameters. Twenty consecutive male patients without respiratory disease scheduled for CABG at the University Hospital of Regensburg were entered into the study. Patients were randomized to postoperative ventilation with the Siemens 300 A/automode ventilator (group A, n = 10) or with the Siemens 300 ventilator (group B, n = 10). All patients were weaned from ventilation according to a standardized protocol. On average, patients in group A were younger and had lower pulmonary artery...Continue Reading

Citations

Aug 20, 2008·Critical Care : the Official Journal of the Critical Care Forum·Mohamad F El-Khatib, Pierre Bou-Khalil
Oct 23, 2012·Medicina intensiva·F Frutos-Vivar, A Esteban
Sep 8, 2012·Clinics in Perinatology·G M Sant'Anna, Martin Keszler
Jun 11, 2014·The Cochrane Database of Systematic Reviews·Louise RoseBronagh Blackwood
Nov 7, 2014·The Cochrane Database of Systematic Reviews·Bronagh BlackwoodPeter O'Halloran
Dec 6, 2007·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Rosane GoldwasserValdelis Okamoto

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