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A rapid genome-wide microRNA screen identifies miR-14 as a modulator of Hedgehog signaling

Cell Reports

Jun 17, 2014

Kevin KimNorbert Perrimon

Abstract

MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression by binding to sequences within the 3' UTR of mRNAs. Because miRNAs bind to short sequences with partial complementarity, target identification is challenging. To complement the existing target prediction algorithm...read more

Mentioned in this Paper

Hedgehog Proteins
Biochemical Pathway
Transfection
Cell Fate
Untranslated Regions
Genome
Act42A
Actins
Candidate Disease Gene
Receptor Down-Regulation
4
44
Paper Details
References
  • References38
  • Citations8
1234
  • References38
  • Citations8
1

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A rapid genome-wide microRNA screen identifies miR-14 as a modulator of Hedgehog signaling

Cell Reports

Jun 17, 2014

Kevin KimNorbert Perrimon

PMID: 24931604

DOI: 10.1016/j.celrep.2014.05.025

Abstract

MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression by binding to sequences within the 3' UTR of mRNAs. Because miRNAs bind to short sequences with partial complementarity, target identification is challenging. To complement the existing target prediction algorithm...read more

Mentioned in this Paper

Hedgehog Proteins
Biochemical Pathway
Transfection
Cell Fate
Untranslated Regions
Genome
Act42A
Actins
Candidate Disease Gene
Receptor Down-Regulation
4
44

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Tracheal Neoplasms

Tracheal neoplasms are new abnormal growth of tissue in the trachea. Discover the latest research on tracheal neoplasms here.

Signal Transduction & Control of Gene Expression

Expression of genes are thought to be involved in signaling pathways, which are important for cell growth, metabolism, apoptosis and more. It is thought that gene expression plays a part in the signaling pathways that implicates the biological effects of the cell. Here is the latest research on signal transduction and the control of gene expression.

Related Papers

RNA Biology

Identification of human microRNA targets from isolated argonaute protein complexes

RNA BiologyJuly 20, 2007
Michaela BeitzingerGunter Meister
Genes

Computational Methods for MicroRNA Target Prediction

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Paper Details
References
  • References38
  • Citations8
1234
  • References38
  • Citations8
1
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