Abstract
A 46-year-old man presented with a painless firm mass in the eyelid margin of the left lower eyelid, which had been present for 9 years. Biopsy nine years previously had not established a diagnosis. We performed excisional biopsy of the lesion and lateral advancement skin flap for reconstruction of the skin defect. Histopathologic and immunohistochemical findings were consistent with atypical chondroid syringoma with eccrine differentiation. The systemic metastatic work-up was negative, and no recurrence or metastasis was present at 30-month follow-up. Chondroid syringoma is a rare skin tumor that occurs, very rarely, in the eyelids, especially the lower eyelid. Only 26 cases of chondroid syringoma in the periorbital area, including our case, have been reported, with various characteristics. Chondroid syringomas are classified as two types, the apocrine type characterized by tubular and cystic branching lumina lined by two layers of epithelial cells, and the eccrine type, which has small tubular lumina lined by a single layer of epithelial cells. The tumor can have benign, atypical, and malignant variants. Our patient had the atypical variant, which is characterized by benign cytological features, as well as the presence of inf...Continue Reading
References
Mar 1, 1978·Histopathology·J D Lomax-Smith, J G Azzopardi
Jul 1, 1979·Cancer·J Varela-DuránR Varela-Núnez
Jun 1, 1992·The American Journal of Dermatopathology·L RequenaD J Santa Cruz
Feb 1, 1988·The American Journal of Dermatopathology·G Mazoujian, R Margolis
Nov 1, 1989·Journal of the American Podiatric Medical Association·T G Toback, C J Toback
Feb 1, 1986·The Journal of Hand Surgery : Journal of the British Society for Surgery of the Hand·A Nather, I H Sutherland
Nov 15, 1983·Cancer·E IshimuraK Ichijima
Oct 1, 1993·International Ophthalmology·M MartorinaP Dessanti
Oct 1, 1996·Ophthalmology·S VangveeravongV White
Feb 11, 1999·Annals of Plastic Surgery·T KitazawaK Matsuo
Feb 4, 2003·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Reha YavuzerCem Sezer
Apr 15, 2004·Ophthalmic Plastic and Reconstructive Surgery·John T H MandevilleThaddeus P Dryja
Citations
Jan 1, 2013·Indian Journal of Ophthalmology·M Ashok KumarRamraj Vathsalya
Oct 2, 2014·Wiener medizinische Wochenschrift·U WollinaJ Schönlebe
Feb 9, 2012·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Andrew C WallsDavid E Geist
Aug 13, 2013·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Hui-Chuan Kau, Chieh-Chih Tsai
Jan 9, 2013·Survey of Ophthalmology·Sotiria PaliouraMami Iwamoto
Jul 22, 2009·Annales de pathologie·Mona MlikaSabeh Mzabi
Mar 26, 2016·Diagnostic Pathology·Aileen Azari-Yam, Mohammad Abrishami
Jul 21, 2015·Annales de pathologie·Agathe AounVincent Molinié
Jun 19, 2016·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Norman C Charles, Payal Patel
Jun 4, 2008·Ophthalmic Plastic and Reconstructive Surgery·Valentín HuervaXavier Matías-Guiu
May 21, 2016·Ophthalmic Plastic and Reconstructive Surgery·Lauren E HudsonHans E Grossniklaus
Jan 18, 2019·Journal of Oral and Maxillofacial Pathology : JOMFP·Praveen B ReddyB S Deepak
Nov 7, 2019·Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society·Maya Eiger-MoscovichTatyana Milman
Jun 20, 2020·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·Himanshu Kumar MittalMeena Harsh
Dec 10, 2020·Orbit·Micheal A O'RourkeAlan A McNab
Aug 19, 2007·Current Opinion in Ophthalmology
Jan 1, 2022·BMJ Case Reports·Priyanka V WalvekarSwathi Kaliki