A Rare Case of Hemophagocytic Lymphohistiocytosis in an Adult with Diffuse Large B-Cell Lymphoma

Case Reports in Hematology
Chimezie MbachiBenjamin Mba

Abstract

A 71-year-old Indian female presented with a 3-month history of weight loss and fatigue. Further review confirmed a histological diagnosis of diffuse large B-cell lymphoma. Although bone marrow analysis did not reveal hemophagocytosis, she had some clinical and laboratory pointers to hemophagocytic lymphohistiocytosis (HLH). Her clinical state deteriorated rapidly with development of acute respiratory distress syndrome, diffuse alveolar hemorrhage, and subsequently death.

References

Sep 21, 2001·British Journal of Haematology·M AricòL Moretta
Mar 12, 2015·Blood·Alison M Schram, Nancy Berliner
Jan 4, 2018·Blood Advances·Anna HaydenLuke Y C Chen

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Methods Mentioned

BETA
electrophoresis
biopsy

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