A rare case of hyaline cell-rich atypical chondroid syringoma with divergent differentiation

Indian Journal of Pathology & Microbiology
Smita S MasamattiAparna Narasimha

Abstract

Chondroid syringoma (CS) also known as mixed tumor of the skin, is a rare benign adnexal tumor accounting for < 0.098%. Epithelial cells arranged in cords and tubules set in myxoid or chondroid stroma. Differentiation such as osteoid, sebaceous or mature adipocytes can be seen rarely. Hyaline cell rich is a rare variant of CS composed of cells with eosinophilic hyaline cytoplasm and plasmacytoid features. CS can have benign, atypical and malignant variants. The term atypical mixed tumor is recommended for those tumors which have histological features of malignancy such as infiltrative margin, satellite tumor nodules and tumor necrosis but without proven metastasis. Very few case reports of hyaline cellrich benign CS have been reported in the past, but to the best of our knowledge, possibly it is the first case of atypical hyaline cellrich CS of the little finger in a 65 year-old female showing divergent differentiation.

References

Mar 1, 1978·Histopathology·J D Lomax-Smith, J G Azzopardi
Oct 1, 1984·Journal of Cutaneous Pathology·S E Mills
Nov 1, 1961·Archives of Dermatology·P HIRSCH, E B HELWIG
Oct 2, 2013·International Journal of Applied & Basic Medical Research·Aparna NarasimhaA Supreeth
Jul 13, 2016·Balkan Medical Journal·Fatma MarkoçMurat Aşcı
Aug 12, 2016·Indian Journal of Pathology & Microbiology·Dilip Chandra Barman, Abhijit Bhowmik

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