A rare case of peritoneal disseminated angiosarcoma 20 years after ovarian cancer diagnosis

Gynecologic and Obstetric Investigation
Anita Chudecka-GłazAnna Walecka

Abstract

Angiosarcoma is a rare form of sarcoma which may be either a primary tumor or it may result from previous irradiation because of another tumor. In this paper, we present a case of a female patient diagnosed as having peritoneal disseminated angiosarcoma 20 years after ovarian cancer treatment (surgery, chemotherapy and radiotherapy). The case was very atypical because of an extremely rare peritoneal location and disseminated nature of the changes. Based on the initial histological picture, poorly differentiated cancer metastasis was diagnosed, suggesting a recurrence of the ovarian cancer that had been diagnosed earlier. The time elapsed from the ovarian cancer diagnosis, history of the previous irradiation and concentration of tumor markers were the only additional clinical data provided to the pathologists, which ultimately contributed to a correct diagnosis. The case we present herein shows and emphasizes the importance of proper communication between a clinician and a pathologist, which is a prerequisite for a correct diagnosis and, consequently, for proper treatment of patients. It also confirms the high specificity of the HE4 (human epididymis protein 4) marker in the monitoring of ovarian cancer, which was within normal ...Continue Reading

Citations

Feb 6, 2018·Molecular and Clinical Oncology·Haruko KunitomiDaisuke Aoki
May 26, 2017·BMJ Case Reports·Chin Jin SeoMelissa Teo
Mar 17, 2018·Case Reports in Pathology·Way Chiang, Zofia Tynski

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