A rare case of uterine leiomyosarcoma: a case report.

Journal of Medical Case Reports
Venkata Sujatha VellankiShailaja Kaja

Abstract

Malignant change in a leiomyoma or uterine fibroid is termed leiomyosarcoma. It arises from smooth muscle of the uterus and is a rare tumor that accounts for 2% to 5% of all uterine malignancies. Very few cases are reported in the literature. Our patient did not have any history of genital bleeding, which is the usual presentation in uterine sarcoma. We report an original case report of an unusual presentation of this rare tumor arising from the uterus. A 40-year-old nulliparous woman of South Indian origin presented with a mass in her abdomen for one year with a rapid increase in size over the previous three months. Tumor marker CA-125 was raised, and a computed tomography scan showed a mass arising from the pelvis. An exploratory laparotomy was performed and the histopathology report confirmed the diagnosis of uterine leiomyosarcoma. Because of their rarity, uterine sarcomas are not suitable for screening. Diagnosis is by histopathologic examination and surgery is the only treatment. The prognosis for women with uterine sarcoma primarily depends on the extent of disease at the time of diagnosis and the mitotic index.

References

Jun 1, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·D Lawrence WickerhamCarolyn D Runowicz
Aug 30, 2011·American Journal of Obstetrics and Gynecology·Carolyn D RunowiczNorman Wolmark

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Citations

Jan 9, 2016·International Journal of Surgery Case Reports·Taylan SenolIzzet Yucesoy
Mar 17, 2015·Gynecological Surgery·Hans BrölmannUNKNOWN European Society of Gynaecological Endoscopy (ESGE) steering committee on fibroid morcellation
Sep 6, 2018·BMJ Case Reports·Poh Ting LimJessie Phoon
Apr 26, 2018·BioMed Research International·V TanosR L DeWilde
Jul 16, 2020·Case Reports in Endocrinology·Gabriel Irizarry-VillafañeVíctor Carlo-Chévere
Aug 15, 2017·Case Reports in Oncological Medicine·Jila AgahFateme Moharrer Ahmadi

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Methods Mentioned

BETA
hysterectomy
biopsy

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