PMID: 8972092Dec 1, 1996Paper

A rat model of infection by Salmonella typhimurium or Salm. enteritidis

The Journal of Applied Bacteriology
P J NaughtonA Pusztai

Abstract

Salmonellosis in the rat has many similarities with the disease in humans, with the ileum thought to be the main site of colonization/invasion in both species. Thus, the rat may be a useful way to study the mechanism of infection by these pathogenic bacteria. A series of infection trials carried out with Hooded Lister rats showed that a salmonella infection persisted for an extended period of time and that salmonellae bind to the small intestinal epithelium as early as 4 h after intragastric intubation. Reinfection from the large intestine may not therefore initially play a significant role in the salmonella infection process. The rat model may therefore provide a means to test in vivo interventionist strategies, designed to block binding of the pathogens in the gastrointestinal tract.

References

Jan 1, 1978·Infection·T KalagerC O Solberg
Dec 1, 1978·Infection and Immunity·A W HohmannD Rowley
Nov 1, 1985·The Journal of Infectious Diseases·C E HormaecheH S Joysey
Nov 1, 1987·Infection and Immunity·C L WellsR L Simmons
Jun 1, 1988·Epidemiology and Infection·E G Wilkins, C Roberts
May 1, 1974·The Journal of Experimental Medicine·P B Carter, F M Collins
Feb 1, 1972·Infection and Immunity·F M Collins
May 1, 1970·The Journal of Infectious Diseases·R M MaenzaH Sprinz
Apr 1, 1968·The Journal of Clinical Investigation·J S FordtranN W Carter
Aug 1, 1966·The American Journal of Digestive Diseases·H SprinzT E Woodward
Feb 1, 1983·Infection and Immunity·R FreterK E Carey
Jul 1, 1995·Infection and Immunity·P J Fedorka-CrayJ A Laufer
Mar 1, 1994·Zentralblatt Für Bakteriologie : International Journal of Medical Microbiology·T RadouchevaH Najdenski
Feb 1, 1994·Epidemiology and Infection·E D MintzR V Tauxe
Sep 30, 1995·The Veterinary Record·R H Davies, C Wray
Jul 1, 1959·The Journal of Experimental Medicine·D H BOHMEJ M LEE
Nov 1, 1938·The Journal of Hygiene·A A MilesJ O Irwin
Jan 1, 1977·Journal of Food Protection·Frank L Bryan
Apr 1, 1980·Journal of Food Protection·John H Silliker

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Journal of Infectious Diseases
E L Pesanti, J D Shanley
The Veterinary Record
J Bywater
© 2021 Meta ULC. All rights reserved