A ratiometric 19 F MR-based method for the quantification of Ca2+ using responsive paramagnetic probes

Chemical Communications : Chem Comm
Giuseppe GambinoGoran Angelovski

Abstract

We present a method for assessing the extracellular calcium concentration using 19F chemical shift imaging. Specifically, a custom made calcium-responsive and lanthanide-based 19F MRI probe that undergoes a strong and highly specific modulation of its signal upon coordination with calcium ions was developed and its performance is presented.

References

May 1, 1986·AJR. American Journal of Roentgenology·L Brateman
Dec 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·H L KirschenlohrG A Smith
Apr 1, 1985·Physics in Medicine and Biology·A HaaseD Matthaei
Dec 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·G A SmithP G Morris
Jun 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·T R BrownK Ugurbil
Apr 1, 1996·Neuropediatrics·J Frahm, F Hanefeld
May 30, 1997·Annals of the New York Academy of Sciences·P C Van Zijl, P B Barker
May 23, 1998·NMR in Biomedicine·P S AllenA H Wilman
Nov 24, 2004·Inorganic Chemistry·Silvio AimeMassimo Sisti
Dec 25, 2007·Journal of the American Chemical Society·Shin MizukamiKazuya Kikuchi
May 29, 2008·Chemical Communications : Chem Comm·Alan M KenwrightDavid G Smith
Jul 8, 2008·Chembiochem : a European Journal of Chemical Biology·Goran AngelovskiNikos K Logothetis
May 8, 2009·Molecular Neurodegeneration·Philippe MarambaudValérie Vingtdeux
Nov 19, 2009·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Jelena M Janjic, Eric T Ahrens
Apr 30, 2010·Trends in Biotechnology·Mangala SrinivasI Jolanda M de Vries
Jul 24, 2012·Contrast Media & Molecular Imaging·Aneta KelirisJörn Engelmann
Sep 11, 2012·Biomaterials·Mangala SrinivasMathias Hoehn
Apr 2, 2013·Progress in Nuclear Magnetic Resonance Spectroscopy·Jian-Xin YuRalph P Mason
Aug 3, 2013·Journal of the American Chemical Society·Amnon Bar-ShirMichael T McMahon
Dec 18, 2013·Chemical Reviews·Marie C HeffernThomas J Meade
May 7, 2014·Chemistry : a European Journal·Pascal KadjaneGoran Angelovski
May 27, 2014·Frontiers in Aging Neuroscience·Meghan C McCord, Elias Aizenman
Dec 20, 2014·Journal of the American Chemical Society·Amnon Bar-ShirJeff W M Bulte
Sep 16, 2017·ACS Applied Materials & Interfaces·Adam T PreslarThomas J Meade
May 2, 2018·Nature Nanotechnology·Satoshi OkadaAlan Jasanoff
Jul 28, 2018·Journal of the American Chemical Society·Meng YuEmily L Que
Feb 24, 2019·Nature Communications·Ali BarandovAlan Jasanoff
Sep 25, 2019·Proceedings of the National Academy of Sciences of the United States of America·Tanja SavićGoran Angelovski

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Citations

Dec 4, 2020·Pharmaceuticals·Kyangwi P MalikidogoCélia S Bonnet
Mar 12, 2021·Current Opinion in Chemical Biology·Célia S Bonnet, Éva Tóth
Mar 13, 2021·ACS Applied Materials & Interfaces·Juan Manuel ArangoMónica Carril
Jun 5, 2021·Chemical Physics Reviews·Austin D C MillerArnab Mukherjee
Jul 22, 2021·Chemical Communications : Chem Comm·Tingjuan WuZhong-Xing Jiang
Aug 24, 2021·ACS Sensors·Harun F OzbakirArnab Mukherjee
Oct 12, 2021·Analytical Chemistry·Chang GuoLeyu Wang

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Methods Mentioned

BETA
NMR
chemical exchange
chemical exchange saturation transfer

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