A rational approach to the stool ova and parasite examination

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
John A BrandaMary Jane Ferraro

Abstract

Examination of multiple stool specimens per patient to rule out parasitic infection continues to be recommended in the literature. Attractive alternatives have been proposed, such as examination of a single specimen, but data to support their use have been inconclusive. We reviewed the results of comprehensive stool ova and parasite examinations performed during a 1-year period to determine the incremental value of examining >1 specimen. Next, we implemented rejection criteria, allowing analysis of only a single specimen in most cases, and studied the impact of the change by reviewing data from a subsequent year. Prior to implementation of rejection criteria, 91% of parasites were detected in the first specimen submitted, although many clinical evaluations (72%) involved the submission of only 1 stool specimen. When at least 3 specimens were submitted, the sensitivity of examining the first in the series was 72%. Even the latter sensitivity provides negative predictive values of approximately 98%, approximately 97%, approximately 95%, or approximately 93% when the prevalence of parasites among those tested is 5%, 10%, 15%, or 20%, respectively. Examination of additional specimens after examination of the first specimen that yie...Continue Reading

References

Dec 1, 1979·Journal of Clinical Microbiology·K H YoungC L Spruill
Feb 9, 1978·The New England Journal of Medicine·M S Wolfe
Mar 1, 1975·The American Journal of Tropical Medicine and Hygiene·M Danciger, M Lopez
Dec 1, 1992·Journal of Clinical Microbiology·A J MorrisL B Reller
Aug 1, 1991·Journal of Clinical Microbiology·S P WahlquistJ J Sullivan
Aug 1, 1988·Journal of Clinical Microbiology·C S PetersF E Kocka
Sep 1, 1984·Mayo Clinic Proceedings·R B ThomsonJ H Thompson
Jul 1, 1995·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·D R ShlimP Echeverria
Nov 1, 1993·Journal of Clinical Microbiology·H Marti, J C Koella
Jul 16, 1999·Journal of Clinical Microbiology·C P Cartwright
Feb 1, 1959·American Journal of Clinical Pathology·A D ALICNA, E J FADELL
Feb 7, 2008·Archives of Pathology & Laboratory Medicine·Paul N ValensteinAna K Stankovic

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Citations

May 6, 2009·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·R J ten HoveJ J Verweij
Mar 3, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jon E Rosenblatt
Jun 8, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Thomas Hänscheid, Emilia Valadas
Aug 17, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Y SuputtamongkolN J Beeching
Aug 17, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·John A Branda, Mary Jane Ferraro
Aug 17, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jon P FurunoJon Mark Hirshon
May 29, 2012·Journal of Public Health Management and Practice : JPHMP·Amanda K BrzozowskiAngela M Caliendo
Nov 26, 2010·Journal of Clinical Microbiology·Christopher R PolageCathy A Petti
Dec 20, 2015·Zoonoses and Public Health·F M MunozUNKNOWN Persistent Diarrhea Working Group
Dec 30, 2014·Journal of Clinical Laboratory Analysis·Stacy G BealChristopher D Doern
Sep 21, 2016·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J IntraP Brambilla
Feb 14, 2017·Pediatric Annals·Emily Obringer, Linda Walsh
Apr 6, 2018·International Journal of Environmental Research and Public Health·Marisol GarzónMarta Alves
Nov 8, 2013·Journal of Clinical Microbiology·Ian H McHardyRomney M Humphries
Dec 31, 2008·Current Opinion in Gastroenterology·William E Bennett, Phillip I Tarr
Mar 1, 2019·Cytopathology : Official Journal of the British Society for Clinical Cytology·Neha GargVineeta V Batra
Sep 8, 2017·The Korean Journal of Parasitology·Kun-Yan WeiMu-Han Lü
Aug 28, 2020·Journal of Community Hospital Internal Medicine Perspectives·Mohammad Qasim KhanEugene F Yen
Jun 6, 2018·The American Journal of Gastroenterology·Sonmoon MohapatraCapecomorin S Pitchumoni
May 26, 2017·Pediatric Dermatology·William A BurkeErin M Hurd
Jun 27, 2019·European Journal of Pediatrics·Lenneke SchrierNicole Ritz
Mar 6, 2021·JAMA : the Journal of the American Medical Association·Shana E GleesonMarwan M Azar
May 22, 2020·The World Allergy Organization Journal·Namhee KwonAlvaro A Cruz
Jun 16, 2021·Journal of Gastroenterology and Hepatology·Readon TehKewin Tien Ho Siah

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