PMID: 3770974Jan 1, 1986Paper

A re-examination of ryegrass (Lolium perenne) pollen allergens

International Archives of Allergy and Applied Immunology
S A Ford, B A Baldo

Abstract

Electroblotting of crude ryegrass pollen extracts and purified group I, II and III allergens identified 14 IgE-binding components, 8 of which were previously unrecognized. In addition to allergen groups I, II and III, which are already regarded as clinically important, and on the basis of the frequencies and intensities of IgE binding with sera from 42 ryegrass pollen-allergic patients, proteins with molecular weights (MWs) of 60, 32, 30 and 28 kD were identified as allergens of possible major clinical importance. Six other pollen components with MWs ranging from 23 to 80 kD and which reacted with IgE antibodies in the sera of 33-50% of patients, should also be viewed as proteins with potential clinical relevance for at least a proportion of the patients. The electrophoretic separation patterns of ryegrass pollen extracts in both alkaline and acid gels and IgE-probed membrane transfers produced in this study should serve as useful reference patterns for standardization purposes. In addition, the identification of the complete allergen recognition pattern by individual patients will permit safer and more effective diagnosis and therapy of ryegrass pollen sensitivities.

Citations

May 1, 1995·Molecular Immunology·E TamboriniA Sidoli
Feb 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·M B SinghJ McCluskey
Feb 1, 1992·The Journal of Experimental Medicine·R ValentaD Kraft
Jan 26, 2010·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·C T BernardesE A Taketomi
Sep 15, 1993·European Journal of Biochemistry·M VillalbaR Rodríguez
Apr 1, 1989·The Journal of Allergy and Clinical Immunology·K S JaggiA H Sehon
Dec 12, 1997·European Journal of Biochemistry·E TamboriniP Arosio
Jun 1, 1991·The Journal of Allergy and Clinical Immunology·M YangS S Mohapatra
Jul 1, 1991·Journal of Electron Microscopy Technique·L B Martinez, S M Wick
Apr 8, 2006·International Archives of Allergy and Immunology·Mônica C SopeleteErnesto A Taketomi
May 30, 1998·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·R SluyterW J Britton
Sep 1, 1993·Electrophoresis·G R Donovan, B A Baldo
Aug 27, 1998·Electrophoresis·C Bayard, O Vesterberg
Mar 1, 1989·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·H D ShenS H Han
Sep 1, 1990·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·G R Donovan, B A Baldo
Jan 22, 2003·Immunology and Cell Biology·Mohan B Singh, Prem L Bhalla
Jun 1, 1989·The Journal of Allergy and Clinical Immunology·F MatthiesenH Løwenstein

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