Abstract
Although optimization of atrioventricular and interventricular delays has been demonstrated to improve hemodynamics in patients with cardiac resynchronization therapy (CRT), the required time-consuming procedure discourages its use in clinical practice. Recently, a new method for CRT optimization based on the intracardiac electrogram (IEGM) detected by the implanted leads, has been developed. We evaluated the effectiveness of this method in improving left ventricular (LV) asynchrony and performance using real-time 3D echocardiography (RT3DE). Twenty patients with CRT were prospectively studied. RT3DE was performed before and after IEGM optimization. The standard deviation of the time to the regional LV minimum systolic volume (Tmsv) for all 16 segments (Tmsv 16-SD), six basal and six mid segments (Tmsv 12-SD), and the six basal segments (Tmsv 6-SD) were assessed as a asynchrony indexes. LV end-diastolic and end-systolic volumes (EDV, ESV), stroke volume (SV), ejection fraction (EF), myocardial performance index (MPI), ejection time (ET), and filling time (FT), corrected by R-R interval, were also evaluated. After IEGM optimization, as compared with baseline Tmsv 12-SD and Tmsv 16-SD decreased (P = 0.01, P< 0.001, respectively),...Continue Reading
References
Mar 1, 1997·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·C TeiA J Tajik
Nov 14, 1997·Pacing and Clinical Electrophysiology : PACE·M KindermannH Schieffer
Aug 24, 2000·Heart·Q ZhouD Gibson
Mar 22, 2001·The New England Journal of Medicine·S CazeauUNKNOWN Multisite Stimulation in Cardiomyopathies (MUSTIC) Study Investigators
Oct 5, 2001·Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology·J A Salerno-Uriarte, M Tritto
Jan 30, 2002·Circulation·Cheuk-Man YuChu-Pak Lau
Jun 14, 2002·The New England Journal of Medicine·William T AbrahamUNKNOWN MIRACLE Study Group. Multicenter InSync Randomized Clinical Evaluation
Sep 3, 2002·Journal of the American College of Cardiology·Peter SøgaardPeter T Mortensen
Oct 16, 2002·Circulation·Peter SogaardPeter T Mortensen
Jan 11, 2003·Journal of Cardiovascular Electrophysiology·Zoran B PopovićJames D Thomas
Jun 12, 2003·European Journal of Heart Failure·Giovanni B PeregoGiuseppe Osculati
Aug 9, 2003·Journal of the American College of Cardiology·Xander A A M VerbeekFrits W Prinzen
Dec 17, 2003·Heart·P D LambiaseC A Bucknall
Mar 3, 2004·Circulation·Angelo AuricchioHelmut Klein
Apr 16, 2004·Heart·S KapetanakisM J Monaghan
Jun 15, 2004·International Journal of Cardiology·Alison M DuncanDerek G Gibson
Jun 15, 2004·The American Journal of Cardiology·Berry M van GelderNico H J Pijls
Aug 11, 2004·European Journal of Heart Failure·Boudewijn J KrenningJos R T C Roelandt
Nov 30, 2004·The American Journal of Cardiology·Johannes A van der HeideOtto Kamp
Feb 3, 2005·Pacing and Clinical Electrophysiology : PACE·D O'DonnellW Mohammed
Mar 9, 2005·The New England Journal of Medicine·John G F ClelandUNKNOWN Cardiac Resynchronization-Heart Failure (CARE-HF) Study Investigators
Apr 22, 2005·The American Journal of Cardiology·Maria Cristina PorcianiLuigi Padeletti
Aug 10, 2005·Circulation·S KapetanakisM J Monaghan
Aug 3, 2006·European Heart Journal·Alison M DuncanMichael Y Henein
Aug 8, 2006·European Journal of Heart Failure·Seong-Mi ParkJun Kwan
Dec 19, 2006·Journal of Cardiac Failure·Maria Cristina PorcianiLuigi Padeletti
Jan 3, 2007·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Kevin VernooyFrits W Prinzen
Jan 5, 2007·Pacing and Clinical Electrophysiology : PACE·Haran BurriRené Lerch
Feb 17, 2007·Pacing and Clinical Electrophysiology : PACE·Xiaoyi MinEric S Fain
Feb 23, 2007·Journal of Cardiovascular Electrophysiology·Michael R GoldAlan D Waggoner
Mar 7, 2007·Journal of Cardiovascular Electrophysiology·James H BakerLinda Porterfield
Citations
Aug 30, 2008·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Cinzia ValzaniaFredrik Gadler
Apr 2, 2011·Expert Review of Cardiovascular Therapy·Vikrant NayarPeter J Pugh
Nov 26, 2016·Heart Failure Clinics·Daniel B Cobb, Michael R Gold
Mar 2, 2017·Echocardiography·Gregory J SinnerVincent L Sorrell
Aug 30, 2008·European Heart Journal·Tony StantonJohn J V McMurray
Jan 27, 2009·European Heart Journal·Piercarlo BalloMaurizio Galderisi
Nov 17, 2009·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Fakhar Z KhanDavid P Dutka
Jun 3, 2010·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Margit StraussKarlheinz Seidl
Sep 17, 2011·Herz·C J JensenH Wieneke
Mar 2, 2012·European Heart Journal Cardiovascular Imaging·Sebastiaan A KleijnOtto Kamp
Feb 9, 2012·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Lanfranco AntoniniMassimo Santini
Dec 23, 2011·Journal of Cardiovascular Electrophysiology·Frank A Cuoco, Michael R Gold
Apr 12, 2012·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Chien-Ming ChengShih-Ann Chen
Mar 15, 2011·Heart Failure Reviews·Marc K LahiriClaudio D Schuger
Apr 1, 2016·JACC. Clinical Electrophysiology·Theodora NikolaidouAndrew L Clark
Dec 17, 2008·Current Opinion in Cardiology