Abstract
Currently, endoscopic resection of early colorectal cancer defined as carcinoma with limited invasion of the mucosa (Tis) and submucosa (T1) is possible. However, lymph node spreading increases to 16.2% of cases when tumor invades the submucosa. We analyzed the previously identified factors for lymph node dissemination and recurrence, in our population. We analyzed retrospectively all patients with T1 tumors, treated at our center with endoscopic resection and some with additional surgery between January 2006 and January 2018. Statistical analysis was performed using IBM SPSS Statistics 25.0. One hundred fifty-nine patients were treated with endoscopic resection, 56.6% with additional surgery. The mean age was 68.74 years and 69. 9% were male. All patients who underwent additional surgery presented negative margins and 8.8% presented positive lymph nodes. In a mean follow-up of 23.36 months, 13 patients had relapsed. The risk of relapse did not differ between patients treated with additional surgery from those who only underwent endoscopic resection (p = 0.506). On the other hand, lymph node dissemination (p = 0.007) and a positive endoscopic margin (p = 0.01) were independent risk factors for relapse. There was a positive asso...Continue Reading
References
Mar 28, 2002·Gastrointestinal Endoscopy Clinics of North America·John H Bond
Aug 12, 2003·Zeitschrift für Gastroenterologie·P FrühmorgenG Herrmann
Dec 17, 2009·Cytokine·Farah HussainMona El-Bahrawy
Feb 25, 2010·Annals of Surgical Oncology·Stephen B Edge, Carolyn C Compton
Dec 15, 2010·Journal of Gastroenterology·Hirotoshi KobayashiKenichi Sugihara
Dec 7, 2011·Journal of Gastroenterology and Hepatology·Koichi NakadoiKazuaki Chayama
May 29, 2012·Endoscopy·J H SuhJ H Oh
Jul 26, 2013·Endoscopy·Steven L BoschIris D Nagtegaal
Aug 22, 2013·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Shinji YoshiiMasao Hosokawa
Oct 23, 2013·Annals of Oncology : Official Journal of the European Society for Medical Oncology·R LabiancaUNKNOWN ESMO Guidelines Working Group
Aug 16, 2017·World Journal of Gastroenterology : WJG·Iyad A Issa, Malak Noureddine
Oct 28, 2017·Gut·Anthony LopezCome Lepage
Feb 17, 2018·Gastroenterología y hepatología·Eduardo AlbénizUNKNOWN en nombre del Grupo Español de Resección Endoscópica de la Sociedad Española de Endoscopia Digestiva
Dec 24, 2018·Endoscopy International Open·Giulio AntonelliEmilio Di Giulio
Jan 18, 2019·Gastrointestinal Endoscopy·Armin KuellmerUNKNOWN FTRD study group
Mar 18, 2019·Critical Reviews in Oncology/hematology·Gabriella BuccafuscaPaolo Tralongo
Dec 5, 2019·World Journal of Gastrointestinal Oncology·Aslam R SyedShyam Thakkar