A reappraisal of boundary conditions assumed in pulmonary gas transport models

Respiration Physiology
D A ScrimshireT J Jones

Abstract

Solutions of the classic pulmonary gas transport equation are presented in which a true 'no-flux' boundary condition is specified throughout the respiratory cycle. For the particular models studied it is demonstrated that diffusive mixing is incomplete at end expiration, and that such stratified inhomogeneities give rise to a realistic alveolar plateau for a simulated N2 washout test. The reasons for the disparity of the present findings with those obtained by contemporary workers are explained by critically examining the boundary conditions conventionally assumed at the alveolar wall.

References

Jun 1, 1975·Computers and Biomedical Research, an International Journal·L BakerR A Rhoades
Dec 1, 1972·Computers and Biomedical Research, an International Journal·M Paiva
Sep 1, 1972·The Bulletin of Mathematical Biophysics·P W SchererN M Greene
Aug 1, 1971·Respiration Physiology·G CummingS B Preston
Jan 1, 1966·Respiration Physiology·G CummingI Parker

Citations

Jan 1, 1979·Annals of Biomedical Engineering·D A Scrimshire, R J Loughnane
Jun 1, 1980·Computers and Biomedical Research, an International Journal·M Paiva
Feb 1, 1982·Clinical Physics and Physiological Measurement : an Official Journal of the Hospital Physicists' Association, Deutsche Gesellschaft Für Medizinische Physik and the European Federation of Organisations for Medical Physics·J H Bates, A E McKinnon

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Mathematics
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